Tags

Type your tag names separated by a space and hit enter

Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans.

Abstract

BACKGROUND

Effects of regular exposure to polyphenolic compounds found in tea, leading to improved endothelial function and blood pressure, may reduce cardiovascular disease risk. Controlled trials in humans have found that ingestion of tea can improve endothelial function, but also cause a rapid onset acute increase in blood pressure.

OBJECTIVE

To examine the acute effects of tea consumption on fasting and postprandial vascular function and blood pressure.

METHODS

Endothelium-dependent dilatation of the brachial artery, assessed using ultrasound and blood pressure were measured in 20 participants with a history of coronary artery disease. Measurements were performed at baseline and at 3.5 h (blood pressure) and 4 h (endothelial function) after drinking three cups of black tea or hot water (consumed at time = 0, 1.5 and 3 h) with and without a high-fat (50 g) meal: a total of four treatments administered in random order.

RESULTS

The high-fat meal did not impair endothelial function. In comparison to water alone, endothelium-dependent dilatation was increased by the meal with tea (1.7 (0.4, 3.0)%, P = 0.02), but was not significantly altered by the tea alone (0.7 (-0.6, 2.0)%, P = 0.32). Systolic blood pressure was significantly increased by tea alone in comparison to each of the other three groups: water alone (9.3 (4.5, 14.1) mmHg, P = 0.0003), meal with water (9.8 (5.0, 14.6) mmHg, P = 0.0001) and meal with tea (7.2 (2.4,12.0) mmHg, P = 0.004). Consumption of a meal negated the acute increase in systolic blood pressure found with tea in the fasting state.

CONCLUSION

Consumption of food may alter the acute effects of tea on vascular function and blood pressure.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    University of Western Australia School of Medicine and Pharmacology, Western Australian Institute for Medical Research (WAIMR), Royal Perth Hospital Unit, Perth, Western Australia. jonathan@cyllene.uwa.edu.au

    ,

    Source

    Journal of hypertension 23:1 2005 Jan pg 47-54

    MeSH

    Aged
    Blood Pressure
    Brachial Artery
    Caffeine
    Central Nervous System Stimulants
    Dietary Fats
    Endothelium, Vascular
    Fasting
    Female
    Flavonoids
    Humans
    Hypertension
    Middle Aged
    Phenols
    Polyphenols
    Postprandial Period
    Tea

    Pub Type(s)

    Clinical Trial
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    15643124

    Citation

    Hodgson, Jonathan M., et al. "Acute Effects of Tea On Fasting and Postprandial Vascular Function and Blood Pressure in Humans." Journal of Hypertension, vol. 23, no. 1, 2005, pp. 47-54.
    Hodgson JM, Burke V, Puddey IB. Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans. J Hypertens. 2005;23(1):47-54.
    Hodgson, J. M., Burke, V., & Puddey, I. B. (2005). Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans. Journal of Hypertension, 23(1), pp. 47-54.
    Hodgson JM, Burke V, Puddey IB. Acute Effects of Tea On Fasting and Postprandial Vascular Function and Blood Pressure in Humans. J Hypertens. 2005;23(1):47-54. PubMed PMID: 15643124.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans. AU - Hodgson,Jonathan M, AU - Burke,Valerie, AU - Puddey,Ian B, PY - 2005/1/12/pubmed PY - 2005/6/1/medline PY - 2005/1/12/entrez SP - 47 EP - 54 JF - Journal of hypertension JO - J. Hypertens. VL - 23 IS - 1 N2 - BACKGROUND: Effects of regular exposure to polyphenolic compounds found in tea, leading to improved endothelial function and blood pressure, may reduce cardiovascular disease risk. Controlled trials in humans have found that ingestion of tea can improve endothelial function, but also cause a rapid onset acute increase in blood pressure. OBJECTIVE: To examine the acute effects of tea consumption on fasting and postprandial vascular function and blood pressure. METHODS: Endothelium-dependent dilatation of the brachial artery, assessed using ultrasound and blood pressure were measured in 20 participants with a history of coronary artery disease. Measurements were performed at baseline and at 3.5 h (blood pressure) and 4 h (endothelial function) after drinking three cups of black tea or hot water (consumed at time = 0, 1.5 and 3 h) with and without a high-fat (50 g) meal: a total of four treatments administered in random order. RESULTS: The high-fat meal did not impair endothelial function. In comparison to water alone, endothelium-dependent dilatation was increased by the meal with tea (1.7 (0.4, 3.0)%, P = 0.02), but was not significantly altered by the tea alone (0.7 (-0.6, 2.0)%, P = 0.32). Systolic blood pressure was significantly increased by tea alone in comparison to each of the other three groups: water alone (9.3 (4.5, 14.1) mmHg, P = 0.0003), meal with water (9.8 (5.0, 14.6) mmHg, P = 0.0001) and meal with tea (7.2 (2.4,12.0) mmHg, P = 0.004). Consumption of a meal negated the acute increase in systolic blood pressure found with tea in the fasting state. CONCLUSION: Consumption of food may alter the acute effects of tea on vascular function and blood pressure. SN - 0263-6352 UR - https://www.unboundmedicine.com/medline/citation/15643124/Acute_effects_of_tea_on_fasting_and_postprandial_vascular_function_and_blood_pressure_in_humans_ L2 - http://Insights.ovid.com/pubmed?pmid=15643124 DB - PRIME DP - Unbound Medicine ER -