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[Sero-epidemiological characteristics of antibody to SARS-associated coronavirus in Gansu Province].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2004 Dec; 18(4):325-7.ZS

Abstract

OBJECTIVE

To study the levels of SARS-associated coronavirus IgG antibody of SARS patients, people who closely contacted SARS patients and normal subjects in Gansu province.

METHODS

The levels of SARS-associated coronavirus IgG antibody were measured by ELISA. The material included acute and (or) recovery period sera of 9 SARS patients, sera from 1,109 doctors and nurses closely contacted with SARS patients, laboratory workers, personnel for disease control and prevention, persons who contacted SARS patients, and sera from 978 normal subjects.

RESULTS

SARS coronavirus IgG antibody was detected positive in 6 of the 9 patients, it was still positive in the sera twelve months after recovery; 1 of the closely contacted persons and 3 normal subjects were found positive.

CONCLUSION

The positive rate of SARS coronavirus IgG antibody of patients was consistent with the clinical diagnosis. The low positive rate of the persons who closely contacted SARS patients and normal subjects suggests that SARS probably had no subclinical infection.

Authors+Show Affiliations

Yu DS
Department of Acute Infectious Disease Control and Prevention, Gansu Centers for Disease Control and Prevention, Lanzhou 730000, China.
Fu SH
No affiliation info available
Meng L
No affiliation info available
Jiang JX
No affiliation info available
Wang BT
No affiliation info available
Wang J
No affiliation info available
Wang LH
No affiliation info available
He Y
No affiliation info available
Liang GD
No affiliation info available

MeSH

AdolescentAdultAntibodies, ViralChinaHealth PersonnelHumansImmunoglobulin GInfectious Disease Transmission, Patient-to-ProfessionalMiddle AgedSevere acute respiratory syndrome-related coronavirusSevere Acute Respiratory Syndrome

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15650780

Citation

Yu, De-shan, et al. "[Sero-epidemiological Characteristics of Antibody to SARS-associated Coronavirus in Gansu Province]." Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi = Zhonghua Shiyan He Linchuang Bingduxue Zazhi = Chinese Journal of Experimental and Clinical Virology, vol. 18, no. 4, 2004, pp. 325-7.
Yu DS, Fu SH, Meng L, et al. [Sero-epidemiological characteristics of antibody to SARS-associated coronavirus in Gansu Province]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2004;18(4):325-7.
Yu, D. S., Fu, S. H., Meng, L., Jiang, J. X., Wang, B. T., Wang, J., Wang, L. H., He, Y., & Liang, G. D. (2004). [Sero-epidemiological characteristics of antibody to SARS-associated coronavirus in Gansu Province]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi = Zhonghua Shiyan He Linchuang Bingduxue Zazhi = Chinese Journal of Experimental and Clinical Virology, 18(4), 325-7.
Yu DS, et al. [Sero-epidemiological Characteristics of Antibody to SARS-associated Coronavirus in Gansu Province]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2004;18(4):325-7. PubMed PMID: 15650780.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Sero-epidemiological characteristics of antibody to SARS-associated coronavirus in Gansu Province]. AU - Yu,De-shan, AU - Fu,Shi-hong, AU - Meng,Lei, AU - Jiang,Jian-xiang, AU - Wang,Bing-tao, AU - Wang,Jian, AU - Wang,Li-hua, AU - He,Ying, AU - Liang,Guo-dong, PY - 2005/1/15/pubmed PY - 2006/8/9/medline PY - 2005/1/15/entrez SP - 325 EP - 7 JF - Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology JO - Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi VL - 18 IS - 4 N2 - OBJECTIVE: To study the levels of SARS-associated coronavirus IgG antibody of SARS patients, people who closely contacted SARS patients and normal subjects in Gansu province. METHODS: The levels of SARS-associated coronavirus IgG antibody were measured by ELISA. The material included acute and (or) recovery period sera of 9 SARS patients, sera from 1,109 doctors and nurses closely contacted with SARS patients, laboratory workers, personnel for disease control and prevention, persons who contacted SARS patients, and sera from 978 normal subjects. RESULTS: SARS coronavirus IgG antibody was detected positive in 6 of the 9 patients, it was still positive in the sera twelve months after recovery; 1 of the closely contacted persons and 3 normal subjects were found positive. CONCLUSION: The positive rate of SARS coronavirus IgG antibody of patients was consistent with the clinical diagnosis. The low positive rate of the persons who closely contacted SARS patients and normal subjects suggests that SARS probably had no subclinical infection. SN - 1003-9279 UR - https://www.unboundmedicine.com/medline/citation/15650780/[Sero_epidemiological_characteristics_of_antibody_to_SARS_associated_coronavirus_in_Gansu_Province]_ DB - PRIME DP - Unbound Medicine ER -