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Population-wide benefits of routine vaccination of children against influenza.
Vaccine. 2005 Jan 26; 23(10):1284-93.V

Abstract

Using a stochastic simulation model of influenza transmission, clinical illness, and economic costs, we estimated the population-wide benefits of routinely vaccinating US children (ages 6 months to 18 years) against influenza. Disease burden was projected to decline as a result of both reduced susceptibility to infection among vaccinees and reductions in disease transmission to others in the community. Vaccination of 20% of children would reduce the total number of influenza cases in the US by 46%; 80% coverage would reduce the total number of cases by 91%. Similar reductions were estimated to occur in influenza-related mortality and economic costs.

Authors+Show Affiliations

Weycker D
Policy Analysis Inc., Four Davis Court, Brookline, MA 02445, USA.
Edelsberg J
No affiliation info available
Halloran ME
No affiliation info available
Longini IM
No affiliation info available
Nizam A
No affiliation info available
Ciuryla V
No affiliation info available
Oster G
No affiliation info available

MeSH

AdolescentAdultAge FactorsAlgorithmsChildChild, PreschoolCost SavingsCost of IllnessCosts and Cost AnalysisHospitalizationHumansImmunization ScheduleInfantInfluenza VaccinesInfluenza, HumanMass VaccinationModels, EconomicModels, StatisticalPopulationRisk AssessmentUnited States

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15652671

Citation

Weycker, Derek, et al. "Population-wide Benefits of Routine Vaccination of Children Against Influenza." Vaccine, vol. 23, no. 10, 2005, pp. 1284-93.
Weycker D, Edelsberg J, Halloran ME, et al. Population-wide benefits of routine vaccination of children against influenza. Vaccine. 2005;23(10):1284-93.
Weycker, D., Edelsberg, J., Halloran, M. E., Longini, I. M., Nizam, A., Ciuryla, V., & Oster, G. (2005). Population-wide benefits of routine vaccination of children against influenza. Vaccine, 23(10), 1284-93.
Weycker D, et al. Population-wide Benefits of Routine Vaccination of Children Against Influenza. Vaccine. 2005 Jan 26;23(10):1284-93. PubMed PMID: 15652671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Population-wide benefits of routine vaccination of children against influenza. AU - Weycker,Derek, AU - Edelsberg,John, AU - Halloran,M Elizabeth, AU - Longini,Ira M,Jr AU - Nizam,Azhar, AU - Ciuryla,Vincent, AU - Oster,Gerry, PY - 2004/01/26/received PY - 2004/06/23/revised PY - 2004/08/16/accepted PY - 2005/1/18/pubmed PY - 2005/4/19/medline PY - 2005/1/18/entrez SP - 1284 EP - 93 JF - Vaccine JO - Vaccine VL - 23 IS - 10 N2 - Using a stochastic simulation model of influenza transmission, clinical illness, and economic costs, we estimated the population-wide benefits of routinely vaccinating US children (ages 6 months to 18 years) against influenza. Disease burden was projected to decline as a result of both reduced susceptibility to infection among vaccinees and reductions in disease transmission to others in the community. Vaccination of 20% of children would reduce the total number of influenza cases in the US by 46%; 80% coverage would reduce the total number of cases by 91%. Similar reductions were estimated to occur in influenza-related mortality and economic costs. SN - 0264-410X UR - https://www.unboundmedicine.com/medline/citation/15652671/Population_wide_benefits_of_routine_vaccination_of_children_against_influenza_ DB - PRIME DP - Unbound Medicine ER -