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[Determination of carvacrol and thymol in Mosla chinensis by HPLC].
Zhongguo Zhong Yao Za Zhi. 2004 Nov; 29(11):1030-2.ZZ

Abstract

OBJECTIVE

To establish a quantitative method of determination of carvacrol and thymol in Mosla chinensis.

METHOD

The sample was extracted with 95% ethanol, ODS column was used with methanol-water-acetic acid (60:40:2) as mobile phase. The detection wavelength was set at 274 nm.

RESULT

The linearities of carvacrol and thymol were respectively in the range of 0.23-2.15 microg (r = 0.9999) and 0.39-2.36 microg (r = 0.9999); the average recoveries were 99.9% (RSD 1.4%) and 98.6% (RSD 1.3%); the RSD of repeatability were 1.1% and 1.6%.

CONCLUSION

The method is reliable, and can be used for quality control of M. chinensis.

Authors+Show Affiliations

Ji L
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Wang F
No affiliation info available
Liu YY
No affiliation info available
Tong Y
No affiliation info available
Li XD
No affiliation info available
Feng XF
No affiliation info available
Huang LQ
No affiliation info available
Zhou GP
No affiliation info available

MeSH

Chromatography, High Pressure LiquidCymenesLamiaceaeMonoterpenesPlant Components, AerialPlants, MedicinalQuality ControlThymol

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15656129

Citation

Ji, Li, et al. "[Determination of Carvacrol and Thymol in Mosla Chinensis By HPLC]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 29, no. 11, 2004, pp. 1030-2.
Ji L, Wang F, Liu YY, et al. [Determination of carvacrol and thymol in Mosla chinensis by HPLC]. Zhongguo Zhong Yao Za Zhi. 2004;29(11):1030-2.
Ji, L., Wang, F., Liu, Y. Y., Tong, Y., Li, X. D., Feng, X. F., Huang, L. Q., & Zhou, G. P. (2004). [Determination of carvacrol and thymol in Mosla chinensis by HPLC]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 29(11), 1030-2.
Ji L, et al. [Determination of Carvacrol and Thymol in Mosla Chinensis By HPLC]. Zhongguo Zhong Yao Za Zhi. 2004;29(11):1030-2. PubMed PMID: 15656129.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Determination of carvacrol and thymol in Mosla chinensis by HPLC]. AU - Ji,Li, AU - Wang,Fang, AU - Liu,Yuan-yan, AU - Tong,Yan, AU - Li,Xian-duan, AU - Feng,Xue-feng, AU - Huang,Lu-qi, AU - Zhou,Guo-ping, PY - 2005/1/20/pubmed PY - 2005/6/4/medline PY - 2005/1/20/entrez SP - 1030 EP - 2 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 29 IS - 11 N2 - OBJECTIVE: To establish a quantitative method of determination of carvacrol and thymol in Mosla chinensis. METHOD: The sample was extracted with 95% ethanol, ODS column was used with methanol-water-acetic acid (60:40:2) as mobile phase. The detection wavelength was set at 274 nm. RESULT: The linearities of carvacrol and thymol were respectively in the range of 0.23-2.15 microg (r = 0.9999) and 0.39-2.36 microg (r = 0.9999); the average recoveries were 99.9% (RSD 1.4%) and 98.6% (RSD 1.3%); the RSD of repeatability were 1.1% and 1.6%. CONCLUSION: The method is reliable, and can be used for quality control of M. chinensis. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/15656129/[Determination_of_carvacrol_and_thymol_in_Mosla_chinensis_by_HPLC]_ DB - PRIME DP - Unbound Medicine ER -