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[Iron-deficiency anemia: diagnosis and therapy].
Schweiz Med Wochenschr 1992; 122(13):461-5SM

Abstract

Iron deficiency is the most frequent cause of anemia. The correct diagnosis is based on history, peripheral blood findings and investigations of the iron status. Anemia occurs only when iron stores are empty. Iron deficiency anemia is a microcytic, hypochromic anemia. Red blood cells show poikilo- and anisocytosis with predominance of small erythrocytes. In one third of the patients the anemia is accompanied by slight leukopenia. The platelet counts may be normal, increased or decreased. Iron deficiency is documented by decreased serum iron, increased transferrin and decreased iron saturation. Ferritin below 15 ng/ml confirms the depletion of iron. Once the diagnosis of iron deficiency is established, its cause must be investigated. Pregnancy and bleeding are the most frequent conditions leading to iron deficiency. Therapy of iron deficiency involves treatment of the underlying condition as well as reestablishment of iron stores. Oral therapy is the most safe and economical method of correcting iron deficiency. Parenteral therapy should be confined to exceptional situations.

Authors+Show Affiliations

Departement Innere Medizin, Kantonsspital Basel.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

1566014

Citation

Tichelli, A, et al. "[Iron-deficiency Anemia: Diagnosis and Therapy]." Schweizerische Medizinische Wochenschrift, vol. 122, no. 13, 1992, pp. 461-5.
Tichelli A, Gratwohl A, Speck B. [Iron-deficiency anemia: diagnosis and therapy]. Schweiz Med Wochenschr. 1992;122(13):461-5.
Tichelli, A., Gratwohl, A., & Speck, B. (1992). [Iron-deficiency anemia: diagnosis and therapy]. Schweizerische Medizinische Wochenschrift, 122(13), pp. 461-5.
Tichelli A, Gratwohl A, Speck B. [Iron-deficiency Anemia: Diagnosis and Therapy]. Schweiz Med Wochenschr. 1992 Mar 28;122(13):461-5. PubMed PMID: 1566014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Iron-deficiency anemia: diagnosis and therapy]. AU - Tichelli,A, AU - Gratwohl,A, AU - Speck,B, PY - 1992/3/28/pubmed PY - 1992/3/28/medline PY - 1992/3/28/entrez SP - 461 EP - 5 JF - Schweizerische medizinische Wochenschrift JO - Schweiz Med Wochenschr VL - 122 IS - 13 N2 - Iron deficiency is the most frequent cause of anemia. The correct diagnosis is based on history, peripheral blood findings and investigations of the iron status. Anemia occurs only when iron stores are empty. Iron deficiency anemia is a microcytic, hypochromic anemia. Red blood cells show poikilo- and anisocytosis with predominance of small erythrocytes. In one third of the patients the anemia is accompanied by slight leukopenia. The platelet counts may be normal, increased or decreased. Iron deficiency is documented by decreased serum iron, increased transferrin and decreased iron saturation. Ferritin below 15 ng/ml confirms the depletion of iron. Once the diagnosis of iron deficiency is established, its cause must be investigated. Pregnancy and bleeding are the most frequent conditions leading to iron deficiency. Therapy of iron deficiency involves treatment of the underlying condition as well as reestablishment of iron stores. Oral therapy is the most safe and economical method of correcting iron deficiency. Parenteral therapy should be confined to exceptional situations. SN - 0036-7672 UR - https://www.unboundmedicine.com/medline/citation/1566014/[Iron_deficiency_anemia:_diagnosis_and_therapy]_ L2 - http://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -