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Direct asymmetric aldol reactions catalyzed by (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline.
Chirality. 2005 Feb; 17(2):119-20.C

Abstract

A novel proline derivative, (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline, was conveniently prepared from the naturally occurring (4S)-hydroxy-(S)-proline; 5 mol % of this compound efficiently catalyzes the asymmetric aldol reactions of various benzaldehydes with acetone in excess of acetone as the solvent, giving the aldol adducts in good yields with ee up to 89.8%.

Authors+Show Affiliations

Key Laboratory of Organic Synthesis Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, 1 Shizi Street, Suzhou 215006, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15669082

Citation

Shen, Zongxuan, et al. "Direct Asymmetric Aldol Reactions Catalyzed By (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline." Chirality, vol. 17, no. 2, 2005, pp. 119-20.
Shen Z, Chen W, Jiang H, et al. Direct asymmetric aldol reactions catalyzed by (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline. Chirality. 2005;17(2):119-20.
Shen, Z., Chen, W., Jiang, H., Ding, Y., Luo, X., & Zhang, Y. (2005). Direct asymmetric aldol reactions catalyzed by (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline. Chirality, 17(2), 119-20.
Shen Z, et al. Direct Asymmetric Aldol Reactions Catalyzed By (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline. Chirality. 2005;17(2):119-20. PubMed PMID: 15669082.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Direct asymmetric aldol reactions catalyzed by (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline. AU - Shen,Zongxuan, AU - Chen,Wuhong, AU - Jiang,Hong, AU - Ding,Yi, AU - Luo,Xiaoqing, AU - Zhang,Yawen, PY - 2005/1/26/pubmed PY - 2006/10/28/medline PY - 2005/1/26/entrez SP - 119 EP - 20 JF - Chirality JO - Chirality VL - 17 IS - 2 N2 - A novel proline derivative, (4R)-4-(beta-Naphthalenyl)methoxy-(S)-proline, was conveniently prepared from the naturally occurring (4S)-hydroxy-(S)-proline; 5 mol % of this compound efficiently catalyzes the asymmetric aldol reactions of various benzaldehydes with acetone in excess of acetone as the solvent, giving the aldol adducts in good yields with ee up to 89.8%. SN - 0899-0042 UR - https://www.unboundmedicine.com/medline/citation/15669082/Direct_asymmetric_aldol_reactions_catalyzed_by__4R__4__beta_Naphthalenyl_methoxy__S__proline_ DB - PRIME DP - Unbound Medicine ER -
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