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Incidence of cardiovascular disease in older Americans: the cardiovascular health study.
J Am Geriatr Soc 2005; 53(2):211-8JA

Abstract

OBJECTIVES

To estimate incidence rates of major cardiovascular disease (CVD) in older Americans.

DESIGN

Longitudinal cohort study using prospectively collected data on cardiovascular events.

SETTING

Four U.S. communities in the Cardiovascular Health Study (CHS).

PARTICIPANTS

Five thousand eight hundred eighty-eight participants in CHS, aged 65 or older at enrollment, including 3,393 women (581 African American) and 2,495 men (343 African American).

MEASUREMENTS

At semiannual contacts, participants reported any occurrence of clinical CVD. Medical records were obtained and adjudicated to confirm diagnosis of CVD.

RESULTS

During 10 years of follow-up, incidence of coronary heart disease (CHD) per 1,000 person-years was 39.6 (95% confidence interval (CI)=36.4-43.1) in men and 22.3 (95% CI=20.4-24.2) in women. Cumulative event rates for CHD and myocardial infarction for women aged 75 and older at baseline were similar to those for men aged 65 to 74. The overall incidence of stroke was similar for men and women (14.7 (95% CI=13.0-16.6) and 13.7 (95% CI=12.4-15.1) per 1,000 person-years, respectively), but the risk of stroke increased with age more rapidly in women, resulting in a greater cumulative event rate for stroke in women than in men aged 75 and older. The incidence of congestive heart failure increased 9% with each year of age over 65 and was greater than 6% per year in Caucasian men and women aged 85 and older at baseline. Rates were similar in African Americans and Caucasians.

CONCLUSION

The occurrence of new CVD in older Americans is high, indicating that preventive efforts need to be maintained into older ages.

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    Authors+Show Affiliations

    Arnold AM
    Department of Biostatistics, University of Washington, Seattle, USA. arnolda@u.washington.edu <arnolda@u.washington.edu>
    Psaty BM
    No affiliation info available
    Kuller LH
    No affiliation info available
    Burke GL
    No affiliation info available
    Manolio TA
    No affiliation info available
    Fried LP
    No affiliation info available
    Robbins JA
    No affiliation info available
    Kronmal RA
    No affiliation info available

    MeSH

    African AmericansAge DistributionAgedAged, 80 and overCardiovascular DiseasesEuropean Continental Ancestry GroupFemaleGeriatric AssessmentHumansIncidenceLongitudinal StudiesMaleSex DistributionSurvival RateUnited States

    Pub Type(s)

    Journal Article
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    15673343

    Citation

    Arnold, Alice M., et al. "Incidence of Cardiovascular Disease in Older Americans: the Cardiovascular Health Study." Journal of the American Geriatrics Society, vol. 53, no. 2, 2005, pp. 211-8.
    Arnold AM, Psaty BM, Kuller LH, et al. Incidence of cardiovascular disease in older Americans: the cardiovascular health study. J Am Geriatr Soc. 2005;53(2):211-8.
    Arnold, A. M., Psaty, B. M., Kuller, L. H., Burke, G. L., Manolio, T. A., Fried, L. P., ... Kronmal, R. A. (2005). Incidence of cardiovascular disease in older Americans: the cardiovascular health study. Journal of the American Geriatrics Society, 53(2), pp. 211-8.
    Arnold AM, et al. Incidence of Cardiovascular Disease in Older Americans: the Cardiovascular Health Study. J Am Geriatr Soc. 2005;53(2):211-8. PubMed PMID: 15673343.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Incidence of cardiovascular disease in older Americans: the cardiovascular health study. AU - Arnold,Alice M, AU - Psaty,Bruce M, AU - Kuller,Lewis H, AU - Burke,Gregory L, AU - Manolio,Teri A, AU - Fried,Linda P, AU - Robbins,John A, AU - Kronmal,Richard A, PY - 2005/1/28/pubmed PY - 2005/3/30/medline PY - 2005/1/28/entrez SP - 211 EP - 8 JF - Journal of the American Geriatrics Society JO - J Am Geriatr Soc VL - 53 IS - 2 N2 - OBJECTIVES: To estimate incidence rates of major cardiovascular disease (CVD) in older Americans. DESIGN: Longitudinal cohort study using prospectively collected data on cardiovascular events. SETTING: Four U.S. communities in the Cardiovascular Health Study (CHS). PARTICIPANTS: Five thousand eight hundred eighty-eight participants in CHS, aged 65 or older at enrollment, including 3,393 women (581 African American) and 2,495 men (343 African American). MEASUREMENTS: At semiannual contacts, participants reported any occurrence of clinical CVD. Medical records were obtained and adjudicated to confirm diagnosis of CVD. RESULTS: During 10 years of follow-up, incidence of coronary heart disease (CHD) per 1,000 person-years was 39.6 (95% confidence interval (CI)=36.4-43.1) in men and 22.3 (95% CI=20.4-24.2) in women. Cumulative event rates for CHD and myocardial infarction for women aged 75 and older at baseline were similar to those for men aged 65 to 74. The overall incidence of stroke was similar for men and women (14.7 (95% CI=13.0-16.6) and 13.7 (95% CI=12.4-15.1) per 1,000 person-years, respectively), but the risk of stroke increased with age more rapidly in women, resulting in a greater cumulative event rate for stroke in women than in men aged 75 and older. The incidence of congestive heart failure increased 9% with each year of age over 65 and was greater than 6% per year in Caucasian men and women aged 85 and older at baseline. Rates were similar in African Americans and Caucasians. CONCLUSION: The occurrence of new CVD in older Americans is high, indicating that preventive efforts need to be maintained into older ages. SN - 0002-8614 UR - https://www.unboundmedicine.com/medline/citation/15673343/Incidence_of_cardiovascular_disease_in_older_Americans:_the_cardiovascular_health_study_ L2 - https://doi.org/10.1111/j.1532-5415.2005.53105.x DB - PRIME DP - Unbound Medicine ER -