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Health state utilities for childhood attention-deficit/hyperactivity disorder based on parent preferences in the United kingdom.
Med Decis Making. 2005 Jan-Feb; 25(1):56-70.MD

Abstract

OBJECTIVES

The purpose of this study was to use standard gamble (SG) utility interviews to assess parent preferences for health states of childhood attention-deficit/hyperactivity disorder (ADHD).

METHODS

The study was conducted in August 2003 in London, England. Parents (N=83) of children diagnosed with ADHD completed SG utility interviews, rating their child's current health and 14 hypothetical health states describing untreated ADHD and ADHD treated with a nonstimulant, immediate-release stimulant, or extended-release stimulant. Raw temporary utilities ranging from 0 (worst health) to 1 (best health) were adjusted to a chronic utility scale ranging from 0 (death) to 1 (best health) using a linear transformation. Parents rated the severity of their children's ADHD symptoms using the Attention-Deficit/Hyperactivity Disorder Rating Scale-IV (ADHD-RS) and their children's health-related quality of life using the EuroQol EQ-5D.

RESULTS

Raw and adjusted SG ratings of hypothetical health states ranged from 0.63-0.90 and 0.88-0.96, respectively. Parents' raw SG scores of their child's current health state (mean=0.72) were significantly correlated with inattentive, hyperactive, and overall ADHD symptoms (r=-0.25, -0.27, -0.27; P <0.05) and the EQ-5D visual analogue scale (r=0.26; P <0.05).

CONCLUSION

This UK-based study suggests that parent SG interviews are a valid method for obtaining utilities for child ADHD-related health states. The utilities obtained in this study would be appropriate for use in a cost-utility analysis evaluating the costs and benefits of childhood ADHD treatments in the United Kingdom.

Authors+Show Affiliations

Eli Lilly and Company, Indianapolis, Indiana 46285, USA. Secnik_Kristina@lilly.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15673582

Citation

Secnik, Kristina, et al. "Health State Utilities for Childhood Attention-deficit/hyperactivity Disorder Based On Parent Preferences in the United Kingdom." Medical Decision Making : an International Journal of the Society for Medical Decision Making, vol. 25, no. 1, 2005, pp. 56-70.
Secnik K, Matza LS, Cottrell S, et al. Health state utilities for childhood attention-deficit/hyperactivity disorder based on parent preferences in the United kingdom. Med Decis Making. 2005;25(1):56-70.
Secnik, K., Matza, L. S., Cottrell, S., Edgell, E., Tilden, D., & Mannix, S. (2005). Health state utilities for childhood attention-deficit/hyperactivity disorder based on parent preferences in the United kingdom. Medical Decision Making : an International Journal of the Society for Medical Decision Making, 25(1), 56-70.
Secnik K, et al. Health State Utilities for Childhood Attention-deficit/hyperactivity Disorder Based On Parent Preferences in the United Kingdom. Med Decis Making. 2005 Jan-Feb;25(1):56-70. PubMed PMID: 15673582.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Health state utilities for childhood attention-deficit/hyperactivity disorder based on parent preferences in the United kingdom. AU - Secnik,Kristina, AU - Matza,Louis S, AU - Cottrell,Suzi, AU - Edgell,Eric, AU - Tilden,Dominic, AU - Mannix,Sally, PY - 2005/1/28/pubmed PY - 2005/5/11/medline PY - 2005/1/28/entrez SP - 56 EP - 70 JF - Medical decision making : an international journal of the Society for Medical Decision Making JO - Med Decis Making VL - 25 IS - 1 N2 - OBJECTIVES: The purpose of this study was to use standard gamble (SG) utility interviews to assess parent preferences for health states of childhood attention-deficit/hyperactivity disorder (ADHD). METHODS: The study was conducted in August 2003 in London, England. Parents (N=83) of children diagnosed with ADHD completed SG utility interviews, rating their child's current health and 14 hypothetical health states describing untreated ADHD and ADHD treated with a nonstimulant, immediate-release stimulant, or extended-release stimulant. Raw temporary utilities ranging from 0 (worst health) to 1 (best health) were adjusted to a chronic utility scale ranging from 0 (death) to 1 (best health) using a linear transformation. Parents rated the severity of their children's ADHD symptoms using the Attention-Deficit/Hyperactivity Disorder Rating Scale-IV (ADHD-RS) and their children's health-related quality of life using the EuroQol EQ-5D. RESULTS: Raw and adjusted SG ratings of hypothetical health states ranged from 0.63-0.90 and 0.88-0.96, respectively. Parents' raw SG scores of their child's current health state (mean=0.72) were significantly correlated with inattentive, hyperactive, and overall ADHD symptoms (r=-0.25, -0.27, -0.27; P <0.05) and the EQ-5D visual analogue scale (r=0.26; P <0.05). CONCLUSION: This UK-based study suggests that parent SG interviews are a valid method for obtaining utilities for child ADHD-related health states. The utilities obtained in this study would be appropriate for use in a cost-utility analysis evaluating the costs and benefits of childhood ADHD treatments in the United Kingdom. SN - 0272-989X UR - https://www.unboundmedicine.com/medline/citation/15673582/Health_state_utilities_for_childhood_attention_deficit/hyperactivity_disorder_based_on_parent_preferences_in_the_United_kingdom_ L2 - https://journals.sagepub.com/doi/10.1177/0272989X04273140?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -