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ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis.

Abstract

Renal stones have afflicted humans for millennia but there is still no solution to this problem. This review discusses the laboratory and metabolic aspects of the clinical management of patients with renal stones, both primary and secondary in origin. First, non-pharmacological interventions such as increased fluid intake, decreased protein consumption, dietary changes in sodium, calcium, oxalate, potassium, purine, vitamins, and essential fatty acids are considered. Then specific pharmacological treatment to modify urine calcium, oxalate, urate, citrate, and acidity are considered. Finally, more unusual types of stone are examined.

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  • Authors+Show Affiliations

    Clinical Chemistry Department, Queen's Hospital, Burton on Trent, Staffordshire, UK. tim.reynolds@burtonh-tr.wmids.nhs.uk

    Source

    Journal of clinical pathology 58:2 2005 Feb pg 134-40

    MeSH

    Acidosis, Renal Tubular
    Calcium
    Calcium, Dietary
    Citrates
    Cystinuria
    Diet, Protein-Restricted
    Humans
    Inflammatory Bowel Diseases
    Kidney Calculi
    Oxalates
    Uric Acid
    Urinalysis

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    15677531

    Citation

    Reynolds, T M.. "ACP Best Practice No 181: Chemical Pathology Clinical Investigation and Management of Nephrolithiasis." Journal of Clinical Pathology, vol. 58, no. 2, 2005, pp. 134-40.
    Reynolds TM. ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis. J Clin Pathol. 2005;58(2):134-40.
    Reynolds, T. M. (2005). ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis. Journal of Clinical Pathology, 58(2), pp. 134-40.
    Reynolds TM. ACP Best Practice No 181: Chemical Pathology Clinical Investigation and Management of Nephrolithiasis. J Clin Pathol. 2005;58(2):134-40. PubMed PMID: 15677531.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis. A1 - Reynolds,T M, PY - 2005/1/29/pubmed PY - 2005/3/8/medline PY - 2005/1/29/entrez SP - 134 EP - 40 JF - Journal of clinical pathology JO - J. Clin. Pathol. VL - 58 IS - 2 N2 - Renal stones have afflicted humans for millennia but there is still no solution to this problem. This review discusses the laboratory and metabolic aspects of the clinical management of patients with renal stones, both primary and secondary in origin. First, non-pharmacological interventions such as increased fluid intake, decreased protein consumption, dietary changes in sodium, calcium, oxalate, potassium, purine, vitamins, and essential fatty acids are considered. Then specific pharmacological treatment to modify urine calcium, oxalate, urate, citrate, and acidity are considered. Finally, more unusual types of stone are examined. SN - 0021-9746 UR - https://www.unboundmedicine.com/medline/citation/15677531/full_citation L2 - http://jcp.bmj.com/cgi/pmidlookup?view=long&pmid=15677531 DB - PRIME DP - Unbound Medicine ER -