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Evaluation of the anti-inflammatory and antioxidant activities of di-C-glucoflavones from Lychnophora ericoides (Asteraceae).
Planta Med. 2005 Jan; 71(1):3-6.PM

Abstract

The Brazilian medicinal plant Lychnophora ericoides is commercially available as an analgesic and anti-inflammatory agent. The phytochemical investigation of the leaf polar extract yielded 6,8-di-C-beta-glucosylapigenin (1) and the new compound 6,8-di-C-beta-glucosylchrysin (2). 6,8-Di- C-beta-glucosylapigenin (1) showed significant anti-inflammatory activity in the carrageenan-induced rat paw edema. We did not observe any statistical difference between the two compounds (1 and 2) in inhibiting chemiluminescence in opsonized zymosan-stimulated polymorphonuclear leukocytes, suggesting that the anti-inflammatory property of 6,8-di- C-beta-glucosylapigenin (1) is not related to its antioxidant activity.

Authors+Show Affiliations

Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, USP, Ribeirão Preto, São Paulo, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15678365

Citation

Gobbo-Neto, Leonardo, et al. "Evaluation of the Anti-inflammatory and Antioxidant Activities of di-C-glucoflavones From Lychnophora Ericoides (Asteraceae)." Planta Medica, vol. 71, no. 1, 2005, pp. 3-6.
Gobbo-Neto L, Santos MD, Kanashiro A, et al. Evaluation of the anti-inflammatory and antioxidant activities of di-C-glucoflavones from Lychnophora ericoides (Asteraceae). Planta Med. 2005;71(1):3-6.
Gobbo-Neto, L., Santos, M. D., Kanashiro, A., Almeida, M. C., Lucisano-Valim, Y. M., Lopes, J. L., Souza, G. E., & Lopes, N. P. (2005). Evaluation of the anti-inflammatory and antioxidant activities of di-C-glucoflavones from Lychnophora ericoides (Asteraceae). Planta Medica, 71(1), 3-6.
Gobbo-Neto L, et al. Evaluation of the Anti-inflammatory and Antioxidant Activities of di-C-glucoflavones From Lychnophora Ericoides (Asteraceae). Planta Med. 2005;71(1):3-6. PubMed PMID: 15678365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the anti-inflammatory and antioxidant activities of di-C-glucoflavones from Lychnophora ericoides (Asteraceae). AU - Gobbo-Neto,Leonardo, AU - Santos,Michel D, AU - Kanashiro,Alexandre, AU - Almeida,Maria C, AU - Lucisano-Valim,Yara M, AU - Lopes,João L, AU - Souza,Glória E, AU - Lopes,Norberto P, PY - 2005/1/29/pubmed PY - 2005/3/30/medline PY - 2005/1/29/entrez SP - 3 EP - 6 JF - Planta medica JO - Planta Med. VL - 71 IS - 1 N2 - The Brazilian medicinal plant Lychnophora ericoides is commercially available as an analgesic and anti-inflammatory agent. The phytochemical investigation of the leaf polar extract yielded 6,8-di-C-beta-glucosylapigenin (1) and the new compound 6,8-di-C-beta-glucosylchrysin (2). 6,8-Di- C-beta-glucosylapigenin (1) showed significant anti-inflammatory activity in the carrageenan-induced rat paw edema. We did not observe any statistical difference between the two compounds (1 and 2) in inhibiting chemiluminescence in opsonized zymosan-stimulated polymorphonuclear leukocytes, suggesting that the anti-inflammatory property of 6,8-di- C-beta-glucosylapigenin (1) is not related to its antioxidant activity. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/15678365/Evaluation_of_the_anti_inflammatory_and_antioxidant_activities_of_di_C_glucoflavones_from_Lychnophora_ericoides__Asteraceae__ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2005-837742 DB - PRIME DP - Unbound Medicine ER -