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Role of multiple induced sputum examination in the diagnosis of Pneumocystis carinii pneumonia.

Abstract

We evaluated the usefulness of repeated nebulized saline induced sputum examinations among 60 HIV infected patients clinically suspected to have Pneumocystis carinii pneumonia (PCP). We found that the first sample was positive for 15 episodes (21.4%); the second sample was positive in 33 episodes (47.1%); the third sample was positive in 22 episodes (31.4%). Repeated nebulized saline induced sputum examination imporved the yield of Pneumocystis carinii and enhanced the sensitivity of a positive result. This technique is simple, cost-effective, non-invasive, and reliable. We recommend the examination of multiple induced samples of nebulized saline induced sputum in all HIV infected patients with suspected PCP. This recommendation may decrease the need for invasive procedures.

Authors+Show Affiliations

Department of Medicine, Kasturba Medical College, Mangalore, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Validation Study

Language

eng

PubMed ID

15689091

Citation

Narasimha, P D., et al. "Role of Multiple Induced Sputum Examination in the Diagnosis of Pneumocystis Carinii Pneumonia." The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 35, no. 3, 2004, pp. 702-4.
Narasimha PD, Prabha MR, Harsha AB, et al. Role of multiple induced sputum examination in the diagnosis of Pneumocystis carinii pneumonia. Southeast Asian J Trop Med Public Health. 2004;35(3):702-4.
Narasimha, P. D., Prabha, M. R., Harsha, A. B., Thomas, R. J., Shenoy, S., & Chakrapani, M. (2004). Role of multiple induced sputum examination in the diagnosis of Pneumocystis carinii pneumonia. The Southeast Asian Journal of Tropical Medicine and Public Health, 35(3), 702-4.
Narasimha PD, et al. Role of Multiple Induced Sputum Examination in the Diagnosis of Pneumocystis Carinii Pneumonia. Southeast Asian J Trop Med Public Health. 2004;35(3):702-4. PubMed PMID: 15689091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of multiple induced sputum examination in the diagnosis of Pneumocystis carinii pneumonia. AU - Narasimha,P D, AU - Prabha,M R Adhikari, AU - Harsha,A B, AU - Thomas,R John, AU - Shenoy,Shalini, AU - Chakrapani,M, PY - 2005/2/4/pubmed PY - 2005/6/1/medline PY - 2005/2/4/entrez SP - 702 EP - 4 JF - The Southeast Asian journal of tropical medicine and public health JO - Southeast Asian J Trop Med Public Health VL - 35 IS - 3 N2 - We evaluated the usefulness of repeated nebulized saline induced sputum examinations among 60 HIV infected patients clinically suspected to have Pneumocystis carinii pneumonia (PCP). We found that the first sample was positive for 15 episodes (21.4%); the second sample was positive in 33 episodes (47.1%); the third sample was positive in 22 episodes (31.4%). Repeated nebulized saline induced sputum examination imporved the yield of Pneumocystis carinii and enhanced the sensitivity of a positive result. This technique is simple, cost-effective, non-invasive, and reliable. We recommend the examination of multiple induced samples of nebulized saline induced sputum in all HIV infected patients with suspected PCP. This recommendation may decrease the need for invasive procedures. SN - 0125-1562 UR - https://www.unboundmedicine.com/medline/citation/15689091/Role_of_multiple_induced_sputum_examination_in_the_diagnosis_of_Pneumocystis_carinii_pneumonia_ DB - PRIME DP - Unbound Medicine ER -