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Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction.
Laryngoscope 2005; 115(2):363-5L

Abstract

OBJECTIVE

To compare the effectiveness of ciprofloxacin and oxymetazoline solutions instilled after tympanostomy tube placement in the prevention of postoperative otorrhea and tube occlusion.

STUDY DESIGN

Prospective cross-sectional series.

METHODS

We reviewed all bilateral myringotomy and tube placement operations performed by two full-time attending pediatric otolaryngologists during a 9 month period. Data from 488 patients who underwent surgery for otitis media were collected. Demographic and clinical variables including age, sex, number of tube insertions in the past, previous adenoidectomy, type of effusion present at surgery, and type of drop prescribed postoperatively were recorded. All patients were evaluated in the office 2 to 4 weeks postoperatively. Multivariate logistic regression analysis was used to estimate the relationship of these variables with the occurrence of otorrhea and tube patency. Odds ratios were calculated.

RESULTS

No significant differences in postoperative otorrhea or tube patency were found between ciprofloxacin (Ciloxan) and oxymetazoline solutions (Afrin, Visine LR).

CONCLUSION

Oxymetazoline and ciprofloxacin solutions are equivalent in the prevention of postoperative otorrhea and tube occlusion after tympanostomy tube placement. The implications for medication cost and potential adverse reactions are discussed.

Authors+Show Affiliations

Departments of Otolaryngology-Head and Neck Surgery , Temple University School of Medicine, Philadelphia, PA 19140, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

15689767

Citation

Kumar, Veena V., et al. "Oxymetazoline Is Equivalent to Ciprofloxacin in Preventing Postoperative Otorrhea or Tympanostomy Tube Obstruction." The Laryngoscope, vol. 115, no. 2, 2005, pp. 363-5.
Kumar VV, Gaughan J, Isaacson G, et al. Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction. Laryngoscope. 2005;115(2):363-5.
Kumar, V. V., Gaughan, J., Isaacson, G., & Szeremeta, W. (2005). Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction. The Laryngoscope, 115(2), pp. 363-5.
Kumar VV, et al. Oxymetazoline Is Equivalent to Ciprofloxacin in Preventing Postoperative Otorrhea or Tympanostomy Tube Obstruction. Laryngoscope. 2005;115(2):363-5. PubMed PMID: 15689767.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oxymetazoline is equivalent to ciprofloxacin in preventing postoperative otorrhea or tympanostomy tube obstruction. AU - Kumar,Veena V, AU - Gaughan,John, AU - Isaacson,Glenn, AU - Szeremeta,Wasyl, PY - 2005/2/4/pubmed PY - 2005/3/8/medline PY - 2005/2/4/entrez SP - 363 EP - 5 JF - The Laryngoscope JO - Laryngoscope VL - 115 IS - 2 N2 - OBJECTIVE: To compare the effectiveness of ciprofloxacin and oxymetazoline solutions instilled after tympanostomy tube placement in the prevention of postoperative otorrhea and tube occlusion. STUDY DESIGN: Prospective cross-sectional series. METHODS: We reviewed all bilateral myringotomy and tube placement operations performed by two full-time attending pediatric otolaryngologists during a 9 month period. Data from 488 patients who underwent surgery for otitis media were collected. Demographic and clinical variables including age, sex, number of tube insertions in the past, previous adenoidectomy, type of effusion present at surgery, and type of drop prescribed postoperatively were recorded. All patients were evaluated in the office 2 to 4 weeks postoperatively. Multivariate logistic regression analysis was used to estimate the relationship of these variables with the occurrence of otorrhea and tube patency. Odds ratios were calculated. RESULTS: No significant differences in postoperative otorrhea or tube patency were found between ciprofloxacin (Ciloxan) and oxymetazoline solutions (Afrin, Visine LR). CONCLUSION: Oxymetazoline and ciprofloxacin solutions are equivalent in the prevention of postoperative otorrhea and tube occlusion after tympanostomy tube placement. The implications for medication cost and potential adverse reactions are discussed. SN - 0023-852X UR - https://www.unboundmedicine.com/medline/citation/15689767/Oxymetazoline_is_equivalent_to_ciprofloxacin_in_preventing_postoperative_otorrhea_or_tympanostomy_tube_obstruction_ L2 - https://doi.org/10.1097/01.mlg.0000154746.55937.4d DB - PRIME DP - Unbound Medicine ER -