Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2430-5.PN
Abstract
The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic analysis suggested an independent viral invasion from animal to human in this new episode. Combining all existing data but excluding singletons, we identified 202 single-nucleotide variations. Among them, 17 are polymorphic in palm civets only. The ratio of nonsynonymous/synonymous nucleotide substitution in palm civets collected 1 yr apart from different geographic locations is very high, suggesting a rapid evolving process of viral proteins in civet as well, much like their adaptation in the human host in the early 2002-2003 epidemic. Major genetic variations in some critical genes, particularly the Spike gene, seemed essential for the transition from animal-to-human transmission to human-to-human transmission, which eventually caused the first severe acute respiratory syndrome outbreak of 2002/2003.
Links
MeSH
Amino Acid SubstitutionAnimalsChinaDisease OutbreaksEvolution, MolecularGenes, ViralHumansMembrane GlycoproteinsPhylogenyPolymorphism, Single NucleotideSevere acute respiratory syndrome-related coronavirusSevere Acute Respiratory SyndromeSpecies SpecificitySpike Glycoprotein, CoronavirusViral Envelope ProteinsViverridaeZoonoses
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Language
eng
PubMed ID
15695582
Clinical Trial Links
Citation
Song, Huai-Dong, et al. "Cross-host Evolution of Severe Acute Respiratory Syndrome Coronavirus in Palm Civet and Human." Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 7, 2005, pp. 2430-5.
Song HD, Tu CC, Zhang GW, et al. Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A. 2005;102(7):2430-5.
Song, H. D., Tu, C. C., Zhang, G. W., Wang, S. Y., Zheng, K., Lei, L. C., Chen, Q. X., Gao, Y. W., Zhou, H. Q., Xiang, H., Zheng, H. J., Chern, S. W., Cheng, F., Pan, C. M., Xuan, H., Chen, S. J., Luo, H. M., Zhou, D. H., Liu, Y. F., ... Zhao, G. P. (2005). Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proceedings of the National Academy of Sciences of the United States of America, 102(7), 2430-5.
Song HD, et al. Cross-host Evolution of Severe Acute Respiratory Syndrome Coronavirus in Palm Civet and Human. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2430-5. PubMed PMID: 15695582.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
AU - Song,Huai-Dong,
AU - Tu,Chang-Chun,
AU - Zhang,Guo-Wei,
AU - Wang,Sheng-Yue,
AU - Zheng,Kui,
AU - Lei,Lian-Cheng,
AU - Chen,Qiu-Xia,
AU - Gao,Yu-Wei,
AU - Zhou,Hui-Qiong,
AU - Xiang,Hua,
AU - Zheng,Hua-Jun,
AU - Chern,Shur-Wern Wang,
AU - Cheng,Feng,
AU - Pan,Chun-Ming,
AU - Xuan,Hua,
AU - Chen,Sai-Juan,
AU - Luo,Hui-Ming,
AU - Zhou,Duan-Hua,
AU - Liu,Yu-Fei,
AU - He,Jian-Feng,
AU - Qin,Peng-Zhe,
AU - Li,Ling-Hui,
AU - Ren,Yu-Qi,
AU - Liang,Wen-Jia,
AU - Yu,Ye-Dong,
AU - Anderson,Larry,
AU - Wang,Ming,
AU - Xu,Rui-Heng,
AU - Wu,Xin-Wei,
AU - Zheng,Huan-Ying,
AU - Chen,Jin-Ding,
AU - Liang,Guodong,
AU - Gao,Yang,
AU - Liao,Ming,
AU - Fang,Ling,
AU - Jiang,Li-Yun,
AU - Li,Hui,
AU - Chen,Fang,
AU - Di,Biao,
AU - He,Li-Juan,
AU - Lin,Jin-Yan,
AU - Tong,Suxiang,
AU - Kong,Xiangang,
AU - Du,Lin,
AU - Hao,Pei,
AU - Tang,Hua,
AU - Bernini,Andrea,
AU - Yu,Xiao-Jing,
AU - Spiga,Ottavia,
AU - Guo,Zong-Ming,
AU - Pan,Hai-Yan,
AU - He,Wei-Zhong,
AU - Manuguerra,Jean-Claude,
AU - Fontanet,Arnaud,
AU - Danchin,Antoine,
AU - Niccolai,Neri,
AU - Li,Yi-Xue,
AU - Wu,Chung-I,
AU - Zhao,Guo-Ping,
Y1 - 2005/02/04/
PY - 2005/2/8/pubmed
PY - 2005/4/14/medline
PY - 2005/2/8/entrez
SP - 2430
EP - 5
JF - Proceedings of the National Academy of Sciences of the United States of America
JO - Proc Natl Acad Sci U S A
VL - 102
IS - 7
N2 - The genomic sequences of severe acute respiratory syndrome coronaviruses from human and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly identical. Phylogenetic analysis suggested an independent viral invasion from animal to human in this new episode. Combining all existing data but excluding singletons, we identified 202 single-nucleotide variations. Among them, 17 are polymorphic in palm civets only. The ratio of nonsynonymous/synonymous nucleotide substitution in palm civets collected 1 yr apart from different geographic locations is very high, suggesting a rapid evolving process of viral proteins in civet as well, much like their adaptation in the human host in the early 2002-2003 epidemic. Major genetic variations in some critical genes, particularly the Spike gene, seemed essential for the transition from animal-to-human transmission to human-to-human transmission, which eventually caused the first severe acute respiratory syndrome outbreak of 2002/2003.
SN - 0027-8424
UR - https://www.unboundmedicine.com/medline/citation/15695582/Cross_host_evolution_of_severe_acute_respiratory_syndrome_coronavirus_in_palm_civet_and_human_
DB - PRIME
DP - Unbound Medicine
ER -
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