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Alcohol hangover: mechanisms and mediators.

Abstract

Hangovers are a frequent, though unpleasant, experience among people who drink to intoxication. Despite the prevalence of hangovers, however, this condition is not well understood scientifically. Multiple possible contributors to the hangover state have been investigated, and researchers have produced evidence that alcohol can directly promote hangover symptoms through its effects on urine production, the gastrointestinal tract, blood sugar concentrations, sleep patterns, and biological rhythms. In addition, researchers postulate that effects related to alcohol's absence after a drinking bout (i.e., withdrawal), alcohol metabolism, and other factors (e.g., biologically active, nonalcohol compounds in beverages; the use of other drugs; certain personality traits; and a family history of alcoholism) also may contribute to the hangover condition. Few of the treatments commonly described for hangover have undergone scientific evaluation.

Links

  • clinical trials
  • Authors+Show Affiliations

    ,

    Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island, USA.

    Source

    MeSH

    Alcohol-Related Disorders
    Alcoholic Intoxication
    Ethanol
    Headache
    Humans
    Substance Withdrawal Syndrome

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    15706734

    Citation

    Swift, R, and D Davidson. "Alcohol Hangover: Mechanisms and Mediators." Alcohol Health and Research World, vol. 22, no. 1, 1998, pp. 54-60.
    Swift R, Davidson D. Alcohol hangover: mechanisms and mediators. Alcohol Health Res World. 1998;22(1):54-60.
    Swift, R., & Davidson, D. (1998). Alcohol hangover: mechanisms and mediators. Alcohol Health and Research World, 22(1), pp. 54-60.
    Swift R, Davidson D. Alcohol Hangover: Mechanisms and Mediators. Alcohol Health Res World. 1998;22(1):54-60. PubMed PMID: 15706734.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Alcohol hangover: mechanisms and mediators. AU - Swift,R, AU - Davidson,D, PY - 2005/2/15/pubmed PY - 2005/3/18/medline PY - 2005/2/15/entrez SP - 54 EP - 60 JF - Alcohol health and research world JO - Alcohol Health Res World VL - 22 IS - 1 N2 - Hangovers are a frequent, though unpleasant, experience among people who drink to intoxication. Despite the prevalence of hangovers, however, this condition is not well understood scientifically. Multiple possible contributors to the hangover state have been investigated, and researchers have produced evidence that alcohol can directly promote hangover symptoms through its effects on urine production, the gastrointestinal tract, blood sugar concentrations, sleep patterns, and biological rhythms. In addition, researchers postulate that effects related to alcohol's absence after a drinking bout (i.e., withdrawal), alcohol metabolism, and other factors (e.g., biologically active, nonalcohol compounds in beverages; the use of other drugs; certain personality traits; and a family history of alcoholism) also may contribute to the hangover condition. Few of the treatments commonly described for hangover have undergone scientific evaluation. SN - 0090-838X UR - https://www.unboundmedicine.com/medline/citation/15706734/full_citation L2 - https://ClinicalTrials.gov/search/term=15706734 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -