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The effect of topically applied progesterone on sebum excretion rate.
Br J Dermatol 1979; 100(6):687-92BJ

Abstract

There is evidence that anti-androgens may help in the treatment of acne vulgaris. We therefore performed a double-blind trial to assess the effect of topically applied progesterone on sebum excretion rate. Thirty-eight patients took part in the trial which was for 3 months. The preparation had no effect in males. However, a significant reduction in sebum excretion rate was found in females, the effect being maximal at the end of the second month. There was a significant loss of effect at the end of the third month and this was not related to deterioration of the progesterone preparation.

Authors

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Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

157150

Citation

Simpson, N B., et al. "The Effect of Topically Applied Progesterone On Sebum Excretion Rate." The British Journal of Dermatology, vol. 100, no. 6, 1979, pp. 687-92.
Simpson NB, Bowden PE, Forster RA, et al. The effect of topically applied progesterone on sebum excretion rate. Br J Dermatol. 1979;100(6):687-92.
Simpson, N. B., Bowden, P. E., Forster, R. A., & Cunliffe, W. J. (1979). The effect of topically applied progesterone on sebum excretion rate. The British Journal of Dermatology, 100(6), pp. 687-92.
Simpson NB, et al. The Effect of Topically Applied Progesterone On Sebum Excretion Rate. Br J Dermatol. 1979;100(6):687-92. PubMed PMID: 157150.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of topically applied progesterone on sebum excretion rate. AU - Simpson,N B, AU - Bowden,P E, AU - Forster,R A, AU - Cunliffe,W J, PY - 1979/6/1/pubmed PY - 1979/6/1/medline PY - 1979/6/1/entrez SP - 687 EP - 92 JF - The British journal of dermatology JO - Br. J. Dermatol. VL - 100 IS - 6 N2 - There is evidence that anti-androgens may help in the treatment of acne vulgaris. We therefore performed a double-blind trial to assess the effect of topically applied progesterone on sebum excretion rate. Thirty-eight patients took part in the trial which was for 3 months. The preparation had no effect in males. However, a significant reduction in sebum excretion rate was found in females, the effect being maximal at the end of the second month. There was a significant loss of effect at the end of the third month and this was not related to deterioration of the progesterone preparation. SN - 0007-0963 UR - https://www.unboundmedicine.com/medline/citation/157150/The_effect_of_topically_applied_progesterone_on_sebum_excretion_rate_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-0963&date=1979&volume=100&issue=6&spage=687 DB - PRIME DP - Unbound Medicine ER -