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Alcohol consumption and other risk factors for self-reported diabetes among middle-aged Japanese: a population-based prospective study in the JPHC study cohort I.
Diabet Med 2005; 22(3):323-31DM

Abstract

AIMS

Few prospective studies have examined the relationship between lifestyle characteristics and the incidence of diabetes mellitus in an Asian general population. This study was undertaken to evaluate the risk factors for Type 2 diabetes in a population-based prospective study of middle-aged Japanese.

METHODS

We investigated 12,913 men and 15,980 women, aged 40-59 years at baseline (year 0), who participated in the Japan Public Health Center-based prospective study on cancer and cardiovascular diseases (JPHC Study) Cohort I. The participants were followed for up to 10 years. Incident cases of diabetes were identified by self-reporting of a physician's diagnosis on two questionnaires sent to each participant, one at year 5 and the second at year 10.

RESULTS

During the 10-year follow-up, 703 men and 482 women reported newly diagnosed diabetes. Age, body mass index (BMI), family history of diabetes and cigarette smoking were independent risk factors in both genders by multivariate analysis. Among men with a BMI < or = 22 kg/m2, a significant positive association was observed between the diabetes incidence and moderate (23.0 < 46.0 g/day) to high (> 46.0 g/day) alcohol consumption, odds ratio 1.91 (95% CI, 1.05-3.46) and 2.89 (1.63-5.11), respectively. Among men with a BMI > 22 kg/m2, a small non-significant increase in odds ratio was observed with alcohol consumption.

CONCLUSIONS

Established risk factors for diabetes in western populations were also identified as predictors of the disease among Japanese. Moderate to high alcohol consumption was positively associated with the incidence of diabetes in Japanese lean (BMI < or = 22 kg/m2) men.

Authors+Show Affiliations

Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15717882

Citation

Waki, K, et al. "Alcohol Consumption and Other Risk Factors for Self-reported Diabetes Among Middle-aged Japanese: a Population-based Prospective Study in the JPHC Study Cohort I." Diabetic Medicine : a Journal of the British Diabetic Association, vol. 22, no. 3, 2005, pp. 323-31.
Waki K, Noda M, Sasaki S, et al. Alcohol consumption and other risk factors for self-reported diabetes among middle-aged Japanese: a population-based prospective study in the JPHC study cohort I. Diabet Med. 2005;22(3):323-31.
Waki, K., Noda, M., Sasaki, S., Matsumura, Y., Takahashi, Y., Isogawa, A., ... Tsugane, S. (2005). Alcohol consumption and other risk factors for self-reported diabetes among middle-aged Japanese: a population-based prospective study in the JPHC study cohort I. Diabetic Medicine : a Journal of the British Diabetic Association, 22(3), pp. 323-31.
Waki K, et al. Alcohol Consumption and Other Risk Factors for Self-reported Diabetes Among Middle-aged Japanese: a Population-based Prospective Study in the JPHC Study Cohort I. Diabet Med. 2005;22(3):323-31. PubMed PMID: 15717882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol consumption and other risk factors for self-reported diabetes among middle-aged Japanese: a population-based prospective study in the JPHC study cohort I. AU - Waki,K, AU - Noda,M, AU - Sasaki,S, AU - Matsumura,Y, AU - Takahashi,Y, AU - Isogawa,A, AU - Ohashi,Y, AU - Kadowaki,T, AU - Tsugane,S, AU - ,, PY - 2005/2/19/pubmed PY - 2005/5/26/medline PY - 2005/2/19/entrez SP - 323 EP - 31 JF - Diabetic medicine : a journal of the British Diabetic Association JO - Diabet. Med. VL - 22 IS - 3 N2 - AIMS: Few prospective studies have examined the relationship between lifestyle characteristics and the incidence of diabetes mellitus in an Asian general population. This study was undertaken to evaluate the risk factors for Type 2 diabetes in a population-based prospective study of middle-aged Japanese. METHODS: We investigated 12,913 men and 15,980 women, aged 40-59 years at baseline (year 0), who participated in the Japan Public Health Center-based prospective study on cancer and cardiovascular diseases (JPHC Study) Cohort I. The participants were followed for up to 10 years. Incident cases of diabetes were identified by self-reporting of a physician's diagnosis on two questionnaires sent to each participant, one at year 5 and the second at year 10. RESULTS: During the 10-year follow-up, 703 men and 482 women reported newly diagnosed diabetes. Age, body mass index (BMI), family history of diabetes and cigarette smoking were independent risk factors in both genders by multivariate analysis. Among men with a BMI < or = 22 kg/m2, a significant positive association was observed between the diabetes incidence and moderate (23.0 < 46.0 g/day) to high (> 46.0 g/day) alcohol consumption, odds ratio 1.91 (95% CI, 1.05-3.46) and 2.89 (1.63-5.11), respectively. Among men with a BMI > 22 kg/m2, a small non-significant increase in odds ratio was observed with alcohol consumption. CONCLUSIONS: Established risk factors for diabetes in western populations were also identified as predictors of the disease among Japanese. Moderate to high alcohol consumption was positively associated with the incidence of diabetes in Japanese lean (BMI < or = 22 kg/m2) men. SN - 0742-3071 UR - https://www.unboundmedicine.com/medline/citation/15717882/Alcohol_consumption_and_other_risk_factors_for_self_reported_diabetes_among_middle_aged_Japanese:_a_population_based_prospective_study_in_the_JPHC_study_cohort_I_ L2 - https://doi.org/10.1111/j.1464-5491.2004.01403.x DB - PRIME DP - Unbound Medicine ER -