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New concepts in the diagnosis and management of neurocysticercosis (Taenia solium).
Am J Trop Med Hyg. 2005 Jan; 72(1):3-9.AJ

Abstract

Human neurocysticercosis, the infection of the nervous system by the larvae of Taenia solium, is a major cause of epileptic seizures and other neurologic morbidity worldwide. The diagnosis and treatment of neurocysticercosis have been considerably improved in recent years. This improvement includes identification and sequencing of specific antigens and development of new assays for laboratory diagnosis, recognition of the frequency and significance of edema around old, calcified cysts (associated to symptomatic episodes), results of a randomized blinded control treatment trial on treatment efficacy for intraparenchymal disease showing a clinical benefit of decreased seizures, and a much better assessment of the frequency and spectrum of cerebrovascular complications. These advances now permit a much better integration of clinical, serologic, and imaging data for diagnosis and therapeutic purposes.

Authors+Show Affiliations

Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru. hgarcia@jhsph.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

15728858

Citation

Garcia, Hector H., et al. "New Concepts in the Diagnosis and Management of Neurocysticercosis (Taenia Solium)." The American Journal of Tropical Medicine and Hygiene, vol. 72, no. 1, 2005, pp. 3-9.
Garcia HH, Del Brutto OH, Nash TE, et al. New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). Am J Trop Med Hyg. 2005;72(1):3-9.
Garcia, H. H., Del Brutto, O. H., Nash, T. E., White, A. C., Tsang, V. C., & Gilman, R. H. (2005). New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). The American Journal of Tropical Medicine and Hygiene, 72(1), 3-9.
Garcia HH, et al. New Concepts in the Diagnosis and Management of Neurocysticercosis (Taenia Solium). Am J Trop Med Hyg. 2005;72(1):3-9. PubMed PMID: 15728858.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New concepts in the diagnosis and management of neurocysticercosis (Taenia solium). AU - Garcia,Hector H, AU - Del Brutto,Oscar H, AU - Nash,Theodore E, AU - White,A Clinton,Jr AU - Tsang,Victor C W, AU - Gilman,Robert H, PY - 2005/2/25/pubmed PY - 2005/5/3/medline PY - 2005/2/25/entrez SP - 3 EP - 9 JF - The American journal of tropical medicine and hygiene JO - Am. J. Trop. Med. Hyg. VL - 72 IS - 1 N2 - Human neurocysticercosis, the infection of the nervous system by the larvae of Taenia solium, is a major cause of epileptic seizures and other neurologic morbidity worldwide. The diagnosis and treatment of neurocysticercosis have been considerably improved in recent years. This improvement includes identification and sequencing of specific antigens and development of new assays for laboratory diagnosis, recognition of the frequency and significance of edema around old, calcified cysts (associated to symptomatic episodes), results of a randomized blinded control treatment trial on treatment efficacy for intraparenchymal disease showing a clinical benefit of decreased seizures, and a much better assessment of the frequency and spectrum of cerebrovascular complications. These advances now permit a much better integration of clinical, serologic, and imaging data for diagnosis and therapeutic purposes. SN - 0002-9637 UR - https://www.unboundmedicine.com/medline/citation/15728858/full_citation L2 - http://www.ajtmh.org/cgi/pmidlookup?view=long&pmid=15728858 DB - PRIME DP - Unbound Medicine ER -