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Multiple sclerosis and nutrition.

Abstract

Benefits from any particular diet in multiple sclerosis (MS) have not yet been proven. It is, however, frequent that malnutrition may potentially exacerbate the symptoms of MS. There is some evidence that a high intake of saturated fat increases the incidence of MS. Epidemiological studies imply that unsaturated fatty acids may have a positive effect on the course of MS. However, the results of controlled studies are ambiguous. A meta-analysis of three small controlled clinical trials suggests a benefit from linoleic acid. Intake of Vitamin D is associated with a lower incidence of MS. In MS, the risk of osteoporosis is high, and prophylactic vitamin D and calcium should be considered at an early stage. The role of minerals, trace elements, antioxidants, vitamins or fish oil is unclear. The possible relationships between diet and MS have not been subjected to adequate study. It seems possible that in the future, diets or dietary supplements may become recommended forms of treatment for MS.

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  • Authors+Show Affiliations

    ,

    Department of Neurology, Klinikum Mannheim of the University of Heidelberg, Mannheim 68167, Germany. s.schwarz@neuro.ma.uni-heidelberg.de

    Source

    MeSH

    Dietary Fats
    Humans
    Incidence
    Multiple Sclerosis
    Nutritional Status
    Risk Factors
    Vitamin D

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    15732263

    Citation

    Schwarz, Stefan, and Hans Leweling. "Multiple Sclerosis and Nutrition." Multiple Sclerosis (Houndmills, Basingstoke, England), vol. 11, no. 1, 2005, pp. 24-32.
    Schwarz S, Leweling H. Multiple sclerosis and nutrition. Mult Scler. 2005;11(1):24-32.
    Schwarz, S., & Leweling, H. (2005). Multiple sclerosis and nutrition. Multiple Sclerosis (Houndmills, Basingstoke, England), 11(1), pp. 24-32.
    Schwarz S, Leweling H. Multiple Sclerosis and Nutrition. Mult Scler. 2005;11(1):24-32. PubMed PMID: 15732263.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Multiple sclerosis and nutrition. AU - Schwarz,Stefan, AU - Leweling,Hans, PY - 2005/3/1/pubmed PY - 2005/3/22/medline PY - 2005/3/1/entrez SP - 24 EP - 32 JF - Multiple sclerosis (Houndmills, Basingstoke, England) JO - Mult. Scler. VL - 11 IS - 1 N2 - Benefits from any particular diet in multiple sclerosis (MS) have not yet been proven. It is, however, frequent that malnutrition may potentially exacerbate the symptoms of MS. There is some evidence that a high intake of saturated fat increases the incidence of MS. Epidemiological studies imply that unsaturated fatty acids may have a positive effect on the course of MS. However, the results of controlled studies are ambiguous. A meta-analysis of three small controlled clinical trials suggests a benefit from linoleic acid. Intake of Vitamin D is associated with a lower incidence of MS. In MS, the risk of osteoporosis is high, and prophylactic vitamin D and calcium should be considered at an early stage. The role of minerals, trace elements, antioxidants, vitamins or fish oil is unclear. The possible relationships between diet and MS have not been subjected to adequate study. It seems possible that in the future, diets or dietary supplements may become recommended forms of treatment for MS. SN - 1352-4585 UR - https://www.unboundmedicine.com/medline/citation/15732263/full_citation L2 - http://journals.sagepub.com/doi/full/10.1191/1352458505ms1119oa?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -