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Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory.
J Sleep Res 2005; 14(1):69-75JS

Abstract

Cognitive deficits in patients with obstructive sleep apnea syndrome (OSAS) are well demonstrated, but the pathophysiology of these deficits is still controversial, as the relationship between OSA severity and cognitive deficits is usually weak. Our study considers the possible relationship between OSA-related cognitive deficits and the overall intellectual function of OSA patients. Forty-seven OSA patients and 36 normal individuals underwent a neuropsychological battery test assessing attention and alertness. According to the resulting IQ score, patients and controls were divided into a high-intelligence group (IQ > or = 90th percentile) and a normal-intelligence group (50 < or = IQ < 90%ile). Between the two patient groups there were no significant differences noticed, regarding OSA severity or sleepiness. High-intelligence patients showed the same attention/alertness performance compared with the high-intelligence controls. On the contrary, patients with normal-intelligence showed attention/alertness decline compared with the normal-intelligence control group. The two patient groups were re-examined with the same battery test after at least 1 year of CPAP treatment. At re-examination neither patient group showed any differences regarding attention and alertness compared with the control groups. We assume that high-intelligence may have a protective effect against OSA-related cognitive decline, perhaps due to increased cognitive reserve.

Authors+Show Affiliations

Sleep Laboratory, Respiratory Medicine Department, Athens University Medical School, Sotiria Hospital for Chest Diseases, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15743336

Citation

Alchanatis, Manos, et al. "Sleep Apnea-related Cognitive Deficits and Intelligence: an Implication of Cognitive Reserve Theory." Journal of Sleep Research, vol. 14, no. 1, 2005, pp. 69-75.
Alchanatis M, Zias N, Deligiorgis N, et al. Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory. J Sleep Res. 2005;14(1):69-75.
Alchanatis, M., Zias, N., Deligiorgis, N., Amfilochiou, A., Dionellis, G., & Orphanidou, D. (2005). Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory. Journal of Sleep Research, 14(1), pp. 69-75.
Alchanatis M, et al. Sleep Apnea-related Cognitive Deficits and Intelligence: an Implication of Cognitive Reserve Theory. J Sleep Res. 2005;14(1):69-75. PubMed PMID: 15743336.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory. AU - Alchanatis,Manos, AU - Zias,Nikolaos, AU - Deligiorgis,Nikolaos, AU - Amfilochiou,Anastasia, AU - Dionellis,Giorgos, AU - Orphanidou,Dora, PY - 2005/3/4/pubmed PY - 2005/7/1/medline PY - 2005/3/4/entrez SP - 69 EP - 75 JF - Journal of sleep research JO - J Sleep Res VL - 14 IS - 1 N2 - Cognitive deficits in patients with obstructive sleep apnea syndrome (OSAS) are well demonstrated, but the pathophysiology of these deficits is still controversial, as the relationship between OSA severity and cognitive deficits is usually weak. Our study considers the possible relationship between OSA-related cognitive deficits and the overall intellectual function of OSA patients. Forty-seven OSA patients and 36 normal individuals underwent a neuropsychological battery test assessing attention and alertness. According to the resulting IQ score, patients and controls were divided into a high-intelligence group (IQ > or = 90th percentile) and a normal-intelligence group (50 < or = IQ < 90%ile). Between the two patient groups there were no significant differences noticed, regarding OSA severity or sleepiness. High-intelligence patients showed the same attention/alertness performance compared with the high-intelligence controls. On the contrary, patients with normal-intelligence showed attention/alertness decline compared with the normal-intelligence control group. The two patient groups were re-examined with the same battery test after at least 1 year of CPAP treatment. At re-examination neither patient group showed any differences regarding attention and alertness compared with the control groups. We assume that high-intelligence may have a protective effect against OSA-related cognitive decline, perhaps due to increased cognitive reserve. SN - 0962-1105 UR - https://www.unboundmedicine.com/medline/citation/15743336/Sleep_apnea_related_cognitive_deficits_and_intelligence:_an_implication_of_cognitive_reserve_theory_ L2 - https://doi.org/10.1111/j.1365-2869.2004.00436.x DB - PRIME DP - Unbound Medicine ER -