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Prevalence of norovirus among visitors from the United States to Mexico and Guatemala who experience traveler's diarrhea.
J Clin Microbiol. 2005 Mar; 43(3):1112-7.JC

Abstract

Traveler's diarrhea (TD) is the most common infectious illness acquired by visitors to developing nations. The purpose of this study was to utilize molecular diagnostic techniques to determine the prevalence of norovirus (NoV) in TD occurring among visitors from the United States to Guatemala and Mexico. Stool samples (n = 54) were collected from 34 TD cases and analyzed for NoV by reverse transcription-PCR and oligoprobe confirmation. The overall prevalence of NoV was 65%. Interestingly, all NoV-positive stool samples were identified as genogroup I NoVs, and time spent at travel destinations was found to be an important factor in determining the frequency of infection (P = 0.003). Eleven NoV-positive stool samples also tested positive for enterotoxigenic Escherichia coli, indicating that dual infections with this leading bacterial cause of TD were very common. Results of this study suggest that NoV infection is a frequent occurrence among travelers to Mexico and Guatemala who experience episodes of TD. In addition, the simple molecular detection method utilized here will serve to facilitate more in-depth epidemiological studies of this emergent viral pathogen in travelers and other at-risk populations.

Authors+Show Affiliations

Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15750070

Citation

Chapin, Amy R., et al. "Prevalence of Norovirus Among Visitors From the United States to Mexico and Guatemala Who Experience Traveler's Diarrhea." Journal of Clinical Microbiology, vol. 43, no. 3, 2005, pp. 1112-7.
Chapin AR, Carpenter CM, Dudley WC, et al. Prevalence of norovirus among visitors from the United States to Mexico and Guatemala who experience traveler's diarrhea. J Clin Microbiol. 2005;43(3):1112-7.
Chapin, A. R., Carpenter, C. M., Dudley, W. C., Gibson, L. C., Pratdesaba, R., Torres, O., Sanchez, D., Belkind-Gerson, J., Nyquist, I., Kärnell, A., Gustafsson, B., Halpern, J. L., Bourgeois, A. L., & Schwab, K. J. (2005). Prevalence of norovirus among visitors from the United States to Mexico and Guatemala who experience traveler's diarrhea. Journal of Clinical Microbiology, 43(3), 1112-7.
Chapin AR, et al. Prevalence of Norovirus Among Visitors From the United States to Mexico and Guatemala Who Experience Traveler's Diarrhea. J Clin Microbiol. 2005;43(3):1112-7. PubMed PMID: 15750070.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of norovirus among visitors from the United States to Mexico and Guatemala who experience traveler's diarrhea. AU - Chapin,Amy R, AU - Carpenter,Colleen M, AU - Dudley,William C, AU - Gibson,Lucy C, AU - Pratdesaba,Rafael, AU - Torres,Olga, AU - Sanchez,Domingo, AU - Belkind-Gerson,Jaime, AU - Nyquist,Irene, AU - Kärnell,Anders, AU - Gustafsson,Bjorn, AU - Halpern,Jane L, AU - Bourgeois,A Louis, AU - Schwab,Kellogg J, PY - 2005/3/8/pubmed PY - 2005/4/15/medline PY - 2005/3/8/entrez SP - 1112 EP - 7 JF - Journal of clinical microbiology JO - J Clin Microbiol VL - 43 IS - 3 N2 - Traveler's diarrhea (TD) is the most common infectious illness acquired by visitors to developing nations. The purpose of this study was to utilize molecular diagnostic techniques to determine the prevalence of norovirus (NoV) in TD occurring among visitors from the United States to Guatemala and Mexico. Stool samples (n = 54) were collected from 34 TD cases and analyzed for NoV by reverse transcription-PCR and oligoprobe confirmation. The overall prevalence of NoV was 65%. Interestingly, all NoV-positive stool samples were identified as genogroup I NoVs, and time spent at travel destinations was found to be an important factor in determining the frequency of infection (P = 0.003). Eleven NoV-positive stool samples also tested positive for enterotoxigenic Escherichia coli, indicating that dual infections with this leading bacterial cause of TD were very common. Results of this study suggest that NoV infection is a frequent occurrence among travelers to Mexico and Guatemala who experience episodes of TD. In addition, the simple molecular detection method utilized here will serve to facilitate more in-depth epidemiological studies of this emergent viral pathogen in travelers and other at-risk populations. SN - 0095-1137 UR - https://www.unboundmedicine.com/medline/citation/15750070/Prevalence_of_norovirus_among_visitors_from_the_United_States_to_Mexico_and_Guatemala_who_experience_traveler's_diarrhea_ L2 - http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=15750070 DB - PRIME DP - Unbound Medicine ER -