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Maternal and fetal outcome in eclamptic patients in Benin City, Nigeria.
J Obstet Gynaecol. 2004 Oct; 24(7):765-8.JO

Abstract

Eclampsia is a well-recognised major cause of maternal death and perinatal morbidity and mortality. The incidence of eclampsia, its presentation patterns, maternal and perinatal outcomes were investigated in a retrospective study conducted at the University of Benin Teaching Hospital, Nigeria over an 8-year period, 1995 - 2002. There were 103 cases of eclampsia of 7835 deliveries, giving an incidence of one in 76 (1.32%). The mean age of the women was 27.1 +/- 5.6 years. Eclampsia significantly (P < 0.001) occurred in nulliparous and unbooked mothers. Eighty-nine (86.4%) of the patients developed fits in the predelivery stage; 85 (83%) of the patients had at least one premonitory symptom including headache (82.4%) visual disturbance (10.6%) and epigastric pain (7%). There were nine stillbirths and 16 early neonatal deaths for a perinatal mortality rate of 214/1000. The major causes of perinatal mortality were prematurity and birth asphyxia. Eleven maternal deaths occurred with a maternal case fatality rate of 10.7% and a maternal mortality ratio from eclampsia of 140/100 000. The clinical causes of deaths were cardiopulmonary failure, acute renal failure, haemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome and cerebrovascular accident. Timely referral of high-risk patients coupled with availability of emergency obstetric and neonatal care services would reduce the incidence eclampsia associated mortality and morbidity in our facility.

Authors+Show Affiliations

Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15763783

Citation

Onuh, S O., and A O. Aisien. "Maternal and Fetal Outcome in Eclamptic Patients in Benin City, Nigeria." Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, vol. 24, no. 7, 2004, pp. 765-8.
Onuh SO, Aisien AO. Maternal and fetal outcome in eclamptic patients in Benin City, Nigeria. J Obstet Gynaecol. 2004;24(7):765-8.
Onuh, S. O., & Aisien, A. O. (2004). Maternal and fetal outcome in eclamptic patients in Benin City, Nigeria. Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 24(7), 765-8.
Onuh SO, Aisien AO. Maternal and Fetal Outcome in Eclamptic Patients in Benin City, Nigeria. J Obstet Gynaecol. 2004;24(7):765-8. PubMed PMID: 15763783.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Maternal and fetal outcome in eclamptic patients in Benin City, Nigeria. AU - Onuh,S O, AU - Aisien,A O, PY - 2005/3/15/pubmed PY - 2005/4/19/medline PY - 2005/3/15/entrez SP - 765 EP - 8 JF - Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology JO - J Obstet Gynaecol VL - 24 IS - 7 N2 - Eclampsia is a well-recognised major cause of maternal death and perinatal morbidity and mortality. The incidence of eclampsia, its presentation patterns, maternal and perinatal outcomes were investigated in a retrospective study conducted at the University of Benin Teaching Hospital, Nigeria over an 8-year period, 1995 - 2002. There were 103 cases of eclampsia of 7835 deliveries, giving an incidence of one in 76 (1.32%). The mean age of the women was 27.1 +/- 5.6 years. Eclampsia significantly (P < 0.001) occurred in nulliparous and unbooked mothers. Eighty-nine (86.4%) of the patients developed fits in the predelivery stage; 85 (83%) of the patients had at least one premonitory symptom including headache (82.4%) visual disturbance (10.6%) and epigastric pain (7%). There were nine stillbirths and 16 early neonatal deaths for a perinatal mortality rate of 214/1000. The major causes of perinatal mortality were prematurity and birth asphyxia. Eleven maternal deaths occurred with a maternal case fatality rate of 10.7% and a maternal mortality ratio from eclampsia of 140/100 000. The clinical causes of deaths were cardiopulmonary failure, acute renal failure, haemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome and cerebrovascular accident. Timely referral of high-risk patients coupled with availability of emergency obstetric and neonatal care services would reduce the incidence eclampsia associated mortality and morbidity in our facility. SN - 0144-3615 UR - https://www.unboundmedicine.com/medline/citation/15763783/Maternal_and_fetal_outcome_in_eclamptic_patients_in_Benin_City_Nigeria_ DB - PRIME DP - Unbound Medicine ER -