Tags

Type your tag names separated by a space and hit enter

Pterygium/pinguecula and the five-year incidence of age-related maculopathy.
Am J Ophthalmol. 2005 Mar; 139(3):536-7.AJ

Abstract

PURPOSE

To assess the relationship between baseline pterygium and pinguecula and the five-year incidence of age-related maculopathy (ARM).

DESIGN

Population-based longitudinal study.

METHODS

The Blue Mountains Eye Study examined 3654 residents aged 49+ years during 1992 to 1994 and then re-examined 2335 (75.1% of survivors) after five years. Retinal photographs were graded using the Wisconsin Age-Related Maculopathy Grading System. Slit-lamp examination recorded pterygium and pinguecula. Eye-specific data were analyzed using generalized estimating equation models.

RESULTS

After adjusting for age, gender, and smoking, eyes with pterygium or previous pterygium surgery had a higher risk of incident late ARM, odds ratio (OR) 3.3, 95% confidence interval (CI) 1.1 to 10.3, early ARM (OR 1.8, CI 1.1 to 2.9) and soft drusen (OR 2.0, CI 1.9 to 3.4), than eyes without pterygium. We found no association between pinguecula and incident ARM.

CONCLUSIONS

This study found that pterygium was associated with a two- to threefold increased risk of incident late and early ARM.

Authors+Show Affiliations

Center for Vision Research, Department of Ophthalmology, University of Sydney, NSW, Australia.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15767067

Citation

Pham, Thuan Quoc, et al. "Pterygium/pinguecula and the Five-year Incidence of Age-related Maculopathy." American Journal of Ophthalmology, vol. 139, no. 3, 2005, pp. 536-7.
Pham TQ, Wang JJ, Rochtchina E, et al. Pterygium/pinguecula and the five-year incidence of age-related maculopathy. Am J Ophthalmol. 2005;139(3):536-7.
Pham, T. Q., Wang, J. J., Rochtchina, E., & Mitchell, P. (2005). Pterygium/pinguecula and the five-year incidence of age-related maculopathy. American Journal of Ophthalmology, 139(3), 536-7.
Pham TQ, et al. Pterygium/pinguecula and the Five-year Incidence of Age-related Maculopathy. Am J Ophthalmol. 2005;139(3):536-7. PubMed PMID: 15767067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pterygium/pinguecula and the five-year incidence of age-related maculopathy. AU - Pham,Thuan Quoc, AU - Wang,Jie Jin, AU - Rochtchina,Elena, AU - Mitchell,Paul, PY - 2004/08/23/accepted PY - 2005/3/16/pubmed PY - 2005/4/5/medline PY - 2005/3/16/entrez SP - 536 EP - 7 JF - American journal of ophthalmology JO - Am. J. Ophthalmol. VL - 139 IS - 3 N2 - PURPOSE: To assess the relationship between baseline pterygium and pinguecula and the five-year incidence of age-related maculopathy (ARM). DESIGN: Population-based longitudinal study. METHODS: The Blue Mountains Eye Study examined 3654 residents aged 49+ years during 1992 to 1994 and then re-examined 2335 (75.1% of survivors) after five years. Retinal photographs were graded using the Wisconsin Age-Related Maculopathy Grading System. Slit-lamp examination recorded pterygium and pinguecula. Eye-specific data were analyzed using generalized estimating equation models. RESULTS: After adjusting for age, gender, and smoking, eyes with pterygium or previous pterygium surgery had a higher risk of incident late ARM, odds ratio (OR) 3.3, 95% confidence interval (CI) 1.1 to 10.3, early ARM (OR 1.8, CI 1.1 to 2.9) and soft drusen (OR 2.0, CI 1.9 to 3.4), than eyes without pterygium. We found no association between pinguecula and incident ARM. CONCLUSIONS: This study found that pterygium was associated with a two- to threefold increased risk of incident late and early ARM. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/15767067/Pterygium/pinguecula_and_the_five_year_incidence_of_age_related_maculopathy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(04)01083-9 DB - PRIME DP - Unbound Medicine ER -