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Sural and radial sensory responses in healthy adults: diagnostic implications for polyneuropathy.
Muscle Nerve. 2005 May; 31(5):628-32.MN

Abstract

We prospectively performed sural and radial sensory nerve conduction studies in 92 healthy subjects, aged between 21 and 88 years, both to determine the lower limits of normal (LLN) and to assess the effects of age and body mass index (BMI) on the sural and radial sensory nerve action potential (SNAP) amplitudes and on the sural/radial amplitude ratio (SRAR). Using the nonparametric bootstrap method to calculate 95% confidence intervals, we found that the 5% LLN values for sural and radial SNAPs were 14 microV and 25.5 microV in subjects aged < or =39 years, 7 microV and 17.4 microV in subjects aged 40-59 years, and 3 microV and 12 microV in subjects aged > or =60 years. The 5% LLN for SRAR for all patients was 0.21. Sural and radial SNAP amplitudes but not SRAR were strongly and inversely correlated with age and BMI. These age-adjusted normal values and revised SRAR will aid in the electrodiagnosis of polyneuropathy.

Authors+Show Affiliations

Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, TCC 810, Boston, Massachusetts 02215, USA. gesper@bidmc.harvard.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15770668

Citation

Esper, Gregory J., et al. "Sural and Radial Sensory Responses in Healthy Adults: Diagnostic Implications for Polyneuropathy." Muscle & Nerve, vol. 31, no. 5, 2005, pp. 628-32.
Esper GJ, Nardin RA, Benatar M, et al. Sural and radial sensory responses in healthy adults: diagnostic implications for polyneuropathy. Muscle Nerve. 2005;31(5):628-32.
Esper, G. J., Nardin, R. A., Benatar, M., Sax, T. W., Acosta, J. A., & Raynor, E. M. (2005). Sural and radial sensory responses in healthy adults: diagnostic implications for polyneuropathy. Muscle & Nerve, 31(5), 628-32.
Esper GJ, et al. Sural and Radial Sensory Responses in Healthy Adults: Diagnostic Implications for Polyneuropathy. Muscle Nerve. 2005;31(5):628-32. PubMed PMID: 15770668.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sural and radial sensory responses in healthy adults: diagnostic implications for polyneuropathy. AU - Esper,Gregory J, AU - Nardin,Rachel A, AU - Benatar,Michael, AU - Sax,Tracy W, AU - Acosta,Juan A, AU - Raynor,Elizabeth M, PY - 2005/3/17/pubmed PY - 2005/6/4/medline PY - 2005/3/17/entrez SP - 628 EP - 32 JF - Muscle & nerve JO - Muscle Nerve VL - 31 IS - 5 N2 - We prospectively performed sural and radial sensory nerve conduction studies in 92 healthy subjects, aged between 21 and 88 years, both to determine the lower limits of normal (LLN) and to assess the effects of age and body mass index (BMI) on the sural and radial sensory nerve action potential (SNAP) amplitudes and on the sural/radial amplitude ratio (SRAR). Using the nonparametric bootstrap method to calculate 95% confidence intervals, we found that the 5% LLN values for sural and radial SNAPs were 14 microV and 25.5 microV in subjects aged < or =39 years, 7 microV and 17.4 microV in subjects aged 40-59 years, and 3 microV and 12 microV in subjects aged > or =60 years. The 5% LLN for SRAR for all patients was 0.21. Sural and radial SNAP amplitudes but not SRAR were strongly and inversely correlated with age and BMI. These age-adjusted normal values and revised SRAR will aid in the electrodiagnosis of polyneuropathy. SN - 0148-639X UR - https://www.unboundmedicine.com/medline/citation/15770668/Sural_and_radial_sensory_responses_in_healthy_adults:_diagnostic_implications_for_polyneuropathy_ L2 - https://doi.org/10.1002/mus.20313 DB - PRIME DP - Unbound Medicine ER -