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Prevalence of Candida albicans and Trichomonas vaginalis in pregnant women in Havana City by an immunologic latex agglutination test.
MedGenMed. 2004 Oct 15; 6(4):50.M

Abstract

We aimed to estimate the prevalence of Candida albicans and Trichomonas vaginalis in immunocompetent pregnant women living in Havana City, Cuba, with or without symptoms of vaginitis, using a sample of 640 women from 6 Gyneco-obstetrics hospitals, which represents 2.5% of total yearly pregnant women. Diagnosis was made using a new latex agglutination kit (Newvagin C-Kure, La Habana, Cuba). Clinical sensitivity and specificity of this assay were validated against culture method, with 467 and 489 clinical specimens for Candida albicans and Trichomonas vaginalis, respectively. Results showed that the kit clinical sensitivity was 100% for Candida albicans and 86.7% for Trichomonas vaginalis compared with a clinical specificity of 93.3% for Candida albicans and 95.1% for Trichomonas vaginalis by culture. The prevalence of candidiasis was determined to be 42.3% (95% confidence interval [CI] 3.8%); the prevalence of trichomoniasis was 9.84% (95% CI 2.3%). In our sample, 48.7% of the women tested negative with respect to both candidiasis and trichomoniasis. Only 6.41% of the cases yielded inconclusive results. The test has high sensitivity, and our results indicate a relatively high prevalence of both infections. However, a significant difference (P < .001) was also observed in candidiasis and trichomoniasis prevalence among hospitals corresponding to the quantity of women with clinical vaginitis. No difference was observed between diabetics and nondiabetics, probably due to the special care of diabetic pregnant women. We conclude that the method is useful for this kind of vaginitis prevalence study and that candidiasis and trichomoniasis prevalences in pregnant women of Havana are 38.5% to 46.2 % (95% CI) and 7.5% to 12.1% (95% CI), respectively.

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Authors+Show Affiliations

Fernández Limia O
National Center for Animal and Plant Diseases, Carretera de Jamaica y Autopista Nacional, San José de las Lajas, La Habana, Cuba.
Lantero MI
No affiliation info available
Betancourt A
No affiliation info available
de Armas E
No affiliation info available
Villoch A
No affiliation info available

MeSH

Candida albicansCandidiasis, VulvovaginalCubaFemaleHumansLatex Fixation TestsPregnancyPregnancy Complications, InfectiousPrevalenceSeroepidemiologic StudiesTrichomonas Vaginitis

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15775877

Citation

Fernández Limia, Octavio, et al. "Prevalence of Candida Albicans and Trichomonas Vaginalis in Pregnant Women in Havana City By an Immunologic Latex Agglutination Test." MedGenMed : Medscape General Medicine, vol. 6, no. 4, 2004, p. 50.
Fernández Limia O, Lantero MI, Betancourt A, et al. Prevalence of Candida albicans and Trichomonas vaginalis in pregnant women in Havana City by an immunologic latex agglutination test. MedGenMed. 2004;6(4):50.
Fernández Limia, O., Lantero, M. I., Betancourt, A., de Armas, E., & Villoch, A. (2004). Prevalence of Candida albicans and Trichomonas vaginalis in pregnant women in Havana City by an immunologic latex agglutination test. MedGenMed : Medscape General Medicine, 6(4), 50.
Fernández Limia O, et al. Prevalence of Candida Albicans and Trichomonas Vaginalis in Pregnant Women in Havana City By an Immunologic Latex Agglutination Test. MedGenMed. 2004 Oct 15;6(4):50. PubMed PMID: 15775877.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of Candida albicans and Trichomonas vaginalis in pregnant women in Havana City by an immunologic latex agglutination test. AU - Fernández Limia,Octavio, AU - Lantero,María Isela, AU - Betancourt,Arsenio, AU - de Armas,Elizabeth, AU - Villoch,Alejandra, Y1 - 2004/10/15/ PY - 2005/3/19/pubmed PY - 2006/10/13/medline PY - 2005/3/19/entrez SP - 50 EP - 50 JF - MedGenMed : Medscape general medicine JO - MedGenMed VL - 6 IS - 4 N2 - We aimed to estimate the prevalence of Candida albicans and Trichomonas vaginalis in immunocompetent pregnant women living in Havana City, Cuba, with or without symptoms of vaginitis, using a sample of 640 women from 6 Gyneco-obstetrics hospitals, which represents 2.5% of total yearly pregnant women. Diagnosis was made using a new latex agglutination kit (Newvagin C-Kure, La Habana, Cuba). Clinical sensitivity and specificity of this assay were validated against culture method, with 467 and 489 clinical specimens for Candida albicans and Trichomonas vaginalis, respectively. Results showed that the kit clinical sensitivity was 100% for Candida albicans and 86.7% for Trichomonas vaginalis compared with a clinical specificity of 93.3% for Candida albicans and 95.1% for Trichomonas vaginalis by culture. The prevalence of candidiasis was determined to be 42.3% (95% confidence interval [CI] 3.8%); the prevalence of trichomoniasis was 9.84% (95% CI 2.3%). In our sample, 48.7% of the women tested negative with respect to both candidiasis and trichomoniasis. Only 6.41% of the cases yielded inconclusive results. The test has high sensitivity, and our results indicate a relatively high prevalence of both infections. However, a significant difference (P < .001) was also observed in candidiasis and trichomoniasis prevalence among hospitals corresponding to the quantity of women with clinical vaginitis. No difference was observed between diabetics and nondiabetics, probably due to the special care of diabetic pregnant women. We conclude that the method is useful for this kind of vaginitis prevalence study and that candidiasis and trichomoniasis prevalences in pregnant women of Havana are 38.5% to 46.2 % (95% CI) and 7.5% to 12.1% (95% CI), respectively. SN - 1531-0132 UR - https://www.unboundmedicine.com/medline/citation/15775877/Prevalence_of_Candida_albicans_and_Trichomonas_vaginalis_in_pregnant_women_in_Havana_City_by_an_immunologic_latex_agglutination_test_ DB - PRIME DP - Unbound Medicine ER -