Tags

Type your tag names separated by a space and hit enter

Neurotoxic marine poisoning.
Lancet Neurol. 2005 Apr; 4(4):219-28.LN

Abstract

Marine poisoning results from the ingestion of marine animals that contain toxic substances and causes substantial illness in coastal regions. Three main clinical syndromes of marine poisoning have important neurological symptoms-ciguatera, tetrodotoxin poisoning, and paralytic shellfish poisoning. Ciguatera is the commonest syndrome of marine poisoning and is characterised by moderate to severe gastrointestinal effects (vomiting, diarrhoea, and abdominal cramps) and neurological effects (myalgia, paraesthesia, cold allodynia, and ataxia), but is rarely lethal. Tetrodotoxin poisoning and paralytic shellfish poisoning are less common but have a higher fatality rate than ciguatera. Mild gastrointestinal effects and a descending paralysis are characteristic of these types of poisoning. In severe poisoning, paralysis rapidly progresses to respiratory failure. Diagnosis of all types of marine poisoning is made from the circumstances of ingestion (type of fish and location) and the clinical effects. Because there are no antidotes, supportive care, including mechanical ventilation in patients with severe paralysis, is the mainstay of treatment.

Authors+Show Affiliations

Tropical Toxicology Unit, Menzies School of Health Research, Charles Darwin University, NT, and Department of Clinical Toxicology and Pharmacology, Newcastle Mater Misericordiae Hospital, NSW, Australia. gsbite@ferntree.comNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15778101

Citation

Isbister, Geoffrey K., and Matthew C. Kiernan. "Neurotoxic Marine Poisoning." The Lancet. Neurology, vol. 4, no. 4, 2005, pp. 219-28.
Isbister GK, Kiernan MC. Neurotoxic marine poisoning. Lancet Neurol. 2005;4(4):219-28.
Isbister, G. K., & Kiernan, M. C. (2005). Neurotoxic marine poisoning. The Lancet. Neurology, 4(4), 219-28.
Isbister GK, Kiernan MC. Neurotoxic Marine Poisoning. Lancet Neurol. 2005;4(4):219-28. PubMed PMID: 15778101.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurotoxic marine poisoning. AU - Isbister,Geoffrey K, AU - Kiernan,Matthew C, PY - 2005/3/22/pubmed PY - 2005/4/22/medline PY - 2005/3/22/entrez SP - 219 EP - 28 JF - The Lancet. Neurology JO - Lancet Neurol VL - 4 IS - 4 N2 - Marine poisoning results from the ingestion of marine animals that contain toxic substances and causes substantial illness in coastal regions. Three main clinical syndromes of marine poisoning have important neurological symptoms-ciguatera, tetrodotoxin poisoning, and paralytic shellfish poisoning. Ciguatera is the commonest syndrome of marine poisoning and is characterised by moderate to severe gastrointestinal effects (vomiting, diarrhoea, and abdominal cramps) and neurological effects (myalgia, paraesthesia, cold allodynia, and ataxia), but is rarely lethal. Tetrodotoxin poisoning and paralytic shellfish poisoning are less common but have a higher fatality rate than ciguatera. Mild gastrointestinal effects and a descending paralysis are characteristic of these types of poisoning. In severe poisoning, paralysis rapidly progresses to respiratory failure. Diagnosis of all types of marine poisoning is made from the circumstances of ingestion (type of fish and location) and the clinical effects. Because there are no antidotes, supportive care, including mechanical ventilation in patients with severe paralysis, is the mainstay of treatment. SN - 1474-4422 UR - https://www.unboundmedicine.com/medline/citation/15778101/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1474-4422(05)70041-7 DB - PRIME DP - Unbound Medicine ER -