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Synthesis of 15R-PGD2: a potential DP2 receptor agonist.
Bioorg Med Chem Lett. 2005 Apr 01; 15(7):1873-6.BM

Abstract

The first total synthesis of 15R-PGD(2)3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE(2). 15R-PGD(2), a potential DP(2) receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases.

Authors+Show Affiliations

Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 W. University Blvd., Melbourne, FL 32901, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15780624

Citation

Kim, Seongjin, et al. "Synthesis of 15R-PGD2: a Potential DP2 Receptor Agonist." Bioorganic & Medicinal Chemistry Letters, vol. 15, no. 7, 2005, pp. 1873-6.
Kim S, Bellone S, Maxey KM, et al. Synthesis of 15R-PGD2: a potential DP2 receptor agonist. Bioorg Med Chem Lett. 2005;15(7):1873-6.
Kim, S., Bellone, S., Maxey, K. M., Powell, W. S., Lee, G. J., & Rokach, J. (2005). Synthesis of 15R-PGD2: a potential DP2 receptor agonist. Bioorganic & Medicinal Chemistry Letters, 15(7), 1873-6.
Kim S, et al. Synthesis of 15R-PGD2: a Potential DP2 Receptor Agonist. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1873-6. PubMed PMID: 15780624.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of 15R-PGD2: a potential DP2 receptor agonist. AU - Kim,Seongjin, AU - Bellone,Sophie, AU - Maxey,Kirk M, AU - Powell,William S, AU - Lee,Gue-Jae, AU - Rokach,Joshua, PY - 2005/01/10/received PY - 2005/02/03/revised PY - 2005/02/04/accepted PY - 2005/3/23/pubmed PY - 2005/8/6/medline PY - 2005/3/23/entrez SP - 1873 EP - 6 JF - Bioorganic & medicinal chemistry letters JO - Bioorg Med Chem Lett VL - 15 IS - 7 N2 - The first total synthesis of 15R-PGD(2)3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE(2). 15R-PGD(2), a potential DP(2) receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases. SN - 0960-894X UR - https://www.unboundmedicine.com/medline/citation/15780624/Synthesis_of_15R_PGD2:_a_potential_DP2_receptor_agonist_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0960-894X(05)00179-4 DB - PRIME DP - Unbound Medicine ER -