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Analysis of the Choristoneura fumiferana nucleopolyhedrovirus genome.
J Gen Virol. 2005 Apr; 86(Pt 4):929-43.JG

Abstract

The double-stranded DNA genome of Choristoneura fumiferana nucleopolyhedrovirus (CfMNPV) was sequenced and analysed in the context of other group I nucleopolyhedroviruses (NPVs). The genome consists of 129,593 bp with a G + C content of 50.1 mol%. A total of 146 open reading frames (ORFs) of greater than 150 bp, and with no or minimal overlap were identified. In addition, five homologous regions were identified containing 7-10 repeats of a 36 bp imperfect palindromic core. Comparison with other completely sequenced baculovirus genomes revealed that 139 of the CfMNPV ORFs have homologues in at least one other baculovirus and seven ORFs are unique to CfMNPV. Of the 117 CfMNPV ORFs common to all group I NPVs, 12 are exclusive to group I NPVs. Overall, CfMNPV is most similar to Orgyia pseudotsugata MNPV based on gene content, arrangement and overall amino acid identity. Unlike other group I baculoviruses, however, CfMNPV encodes a viral enhancing factor (vef) and has two copies of p26.

Authors+Show Affiliations

Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada, N1G 2W1.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15784887

Citation

de Jong, Jondavid G., et al. "Analysis of the Choristoneura Fumiferana Nucleopolyhedrovirus Genome." The Journal of General Virology, vol. 86, no. Pt 4, 2005, pp. 929-43.
de Jong JG, Lauzon HA, Dominy C, et al. Analysis of the Choristoneura fumiferana nucleopolyhedrovirus genome. J Gen Virol. 2005;86(Pt 4):929-43.
de Jong, J. G., Lauzon, H. A., Dominy, C., Poloumienko, A., Carstens, E. B., Arif, B. M., & Krell, P. J. (2005). Analysis of the Choristoneura fumiferana nucleopolyhedrovirus genome. The Journal of General Virology, 86(Pt 4), 929-43.
de Jong JG, et al. Analysis of the Choristoneura Fumiferana Nucleopolyhedrovirus Genome. J Gen Virol. 2005;86(Pt 4):929-43. PubMed PMID: 15784887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of the Choristoneura fumiferana nucleopolyhedrovirus genome. AU - de Jong,Jondavid G, AU - Lauzon,Hilary A M, AU - Dominy,Cliff, AU - Poloumienko,Arkadi, AU - Carstens,Eric B, AU - Arif,Basil M, AU - Krell,Peter J, PY - 2005/3/24/pubmed PY - 2005/5/6/medline PY - 2005/3/24/entrez SP - 929 EP - 43 JF - The Journal of general virology JO - J. Gen. Virol. VL - 86 IS - Pt 4 N2 - The double-stranded DNA genome of Choristoneura fumiferana nucleopolyhedrovirus (CfMNPV) was sequenced and analysed in the context of other group I nucleopolyhedroviruses (NPVs). The genome consists of 129,593 bp with a G + C content of 50.1 mol%. A total of 146 open reading frames (ORFs) of greater than 150 bp, and with no or minimal overlap were identified. In addition, five homologous regions were identified containing 7-10 repeats of a 36 bp imperfect palindromic core. Comparison with other completely sequenced baculovirus genomes revealed that 139 of the CfMNPV ORFs have homologues in at least one other baculovirus and seven ORFs are unique to CfMNPV. Of the 117 CfMNPV ORFs common to all group I NPVs, 12 are exclusive to group I NPVs. Overall, CfMNPV is most similar to Orgyia pseudotsugata MNPV based on gene content, arrangement and overall amino acid identity. Unlike other group I baculoviruses, however, CfMNPV encodes a viral enhancing factor (vef) and has two copies of p26. SN - 0022-1317 UR - https://www.unboundmedicine.com/medline/citation/15784887/Analysis_of_the_Choristoneura_fumiferana_nucleopolyhedrovirus_genome_ L2 - http://jgv.microbiologyresearch.org/pubmed/content/journal/jgv/10.1099/vir.0.80490-0 DB - PRIME DP - Unbound Medicine ER -