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Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction.
Circ J 2005; 69(4):375-9CJ

Abstract

BACKGROUND

The effects of glucose abnormalities on outcomes after percutaneous coronary intervention (PCI) remain unclear. We examined the association between glucose abnormalities and in-hospital outcome in patients undergoing PCI for acute myocardial infarction (AMI).

METHODS AND RESULTS

A total of 849 patients with AMI who were admitted within 12 h after symptom onset and underwent emergency PCI were classified according to the presence or absence of admission hyperglycemia, defined as a blood glucose level on admission of >11 mmol/L and whether they had a history of diabetes mellitus: group 1 (n = 504), non-diabetic patients without admission hyperglycemia; group 2 (n = 111), diabetic patients without admission hyperglycemia; group 3 (n = 87), non-diabetic patients with admission hyperglycemia; and group 4 (n = 147), diabetic patients with admission hyperglycemia. Among groups 1, 2, 3 and 4, in-hospital mortality was 2.6, 2.7, 11.5 and 8.8%, respectively (p < 0.01). Multivariate analysis showed that compared with group 1 patients, the odds ratio (95%confidence interval) for in-hospital mortality among those in groups 2, 3, and 4 were 0.80 (0.24-2.60, p = 0.708), 2.29 (1.10-5.49, p = 0.039), and 2.14 (1.14-4.69, p = 0.048), respectively.

CONCLUSIONS

In-patients undergoing PCI for AMI, admission hyperglycemia, irrespective of the presence or absence of diabetes, is associated with increased in-hospital mortality, whereas diabetes without admission hyperglycemia is not.

Authors+Show Affiliations

Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15791028

Citation

Kosuge, Masami, et al. "Effects of Glucose Abnormalities On In-hospital Outcome After Coronary Intervention for Acute Myocardial Infarction." Circulation Journal : Official Journal of the Japanese Circulation Society, vol. 69, no. 4, 2005, pp. 375-9.
Kosuge M, Kimura K, Kojima S, et al. Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction. Circ J. 2005;69(4):375-9.
Kosuge, M., Kimura, K., Kojima, S., Sakamoto, T., Matsui, K., Ishihara, M., ... Ogawa, H. (2005). Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction. Circulation Journal : Official Journal of the Japanese Circulation Society, 69(4), pp. 375-9.
Kosuge M, et al. Effects of Glucose Abnormalities On In-hospital Outcome After Coronary Intervention for Acute Myocardial Infarction. Circ J. 2005;69(4):375-9. PubMed PMID: 15791028.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of glucose abnormalities on in-hospital outcome after coronary intervention for acute myocardial infarction. AU - Kosuge,Masami, AU - Kimura,Kazuo, AU - Kojima,Sunao, AU - Sakamoto,Tomohiro, AU - Matsui,Kunihiko, AU - Ishihara,Masaharu, AU - Asada,Yujiro, AU - Tei,Chuwa, AU - Miyazaki,Shunichi, AU - Sonoda,Masahiro, AU - Tsuchihashi,Kazufumi, AU - Yamagishi,Masakazu, AU - Ikeda,Yoshihiko, AU - Shirai,Mutsunori, AU - Hiraoka,Hisatoyo, AU - Inoue,Takeshi, AU - Saito,Fumio, AU - Ogawa,Hisao, AU - ,, PY - 2005/3/26/pubmed PY - 2005/10/19/medline PY - 2005/3/26/entrez SP - 375 EP - 9 JF - Circulation journal : official journal of the Japanese Circulation Society JO - Circ. J. VL - 69 IS - 4 N2 - BACKGROUND: The effects of glucose abnormalities on outcomes after percutaneous coronary intervention (PCI) remain unclear. We examined the association between glucose abnormalities and in-hospital outcome in patients undergoing PCI for acute myocardial infarction (AMI). METHODS AND RESULTS: A total of 849 patients with AMI who were admitted within 12 h after symptom onset and underwent emergency PCI were classified according to the presence or absence of admission hyperglycemia, defined as a blood glucose level on admission of >11 mmol/L and whether they had a history of diabetes mellitus: group 1 (n = 504), non-diabetic patients without admission hyperglycemia; group 2 (n = 111), diabetic patients without admission hyperglycemia; group 3 (n = 87), non-diabetic patients with admission hyperglycemia; and group 4 (n = 147), diabetic patients with admission hyperglycemia. Among groups 1, 2, 3 and 4, in-hospital mortality was 2.6, 2.7, 11.5 and 8.8%, respectively (p < 0.01). Multivariate analysis showed that compared with group 1 patients, the odds ratio (95%confidence interval) for in-hospital mortality among those in groups 2, 3, and 4 were 0.80 (0.24-2.60, p = 0.708), 2.29 (1.10-5.49, p = 0.039), and 2.14 (1.14-4.69, p = 0.048), respectively. CONCLUSIONS: In-patients undergoing PCI for AMI, admission hyperglycemia, irrespective of the presence or absence of diabetes, is associated with increased in-hospital mortality, whereas diabetes without admission hyperglycemia is not. SN - 1346-9843 UR - https://www.unboundmedicine.com/medline/citation/15791028/Effects_of_glucose_abnormalities_on_in_hospital_outcome_after_coronary_intervention_for_acute_myocardial_infarction_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/circj/69.375?from=PubMed DB - PRIME DP - Unbound Medicine ER -