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Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole.
Obstet Gynecol. 1992 Jun; 79(6):1020-3.OG

Abstract

In a randomized, double-blind study, 48 women with symptomatic bacterial vaginosis were assigned to receive either 5 g of 2% clindamycin vaginal cream daily or 500 mg metronidazole oral tablets twice a day for 7 days. After completion of therapy, there was no significant difference in cure rates (clindamycin 72% versus metronidazole 87%). One month later, 61% of the patients in each group were still cured. Adverse reactions were mild in both groups. We conclude that clindamycin cream is a safe, well tolerated, and effective alternative to oral metronidazole for treatment of bacterial vaginosis.

Authors+Show Affiliations

Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1579299

Citation

Schmitt, C, et al. "Bacterial Vaginosis: Treatment With Clindamycin Cream Versus Oral Metronidazole." Obstetrics and Gynecology, vol. 79, no. 6, 1992, pp. 1020-3.
Schmitt C, Sobel JD, Meriwether C. Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole. Obstet Gynecol. 1992;79(6):1020-3.
Schmitt, C., Sobel, J. D., & Meriwether, C. (1992). Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole. Obstetrics and Gynecology, 79(6), 1020-3.
Schmitt C, Sobel JD, Meriwether C. Bacterial Vaginosis: Treatment With Clindamycin Cream Versus Oral Metronidazole. Obstet Gynecol. 1992;79(6):1020-3. PubMed PMID: 1579299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole. AU - Schmitt,C, AU - Sobel,J D, AU - Meriwether,C, PY - 1992/6/1/pubmed PY - 1992/6/1/medline PY - 1992/6/1/entrez SP - 1020 EP - 3 JF - Obstetrics and gynecology JO - Obstet Gynecol VL - 79 IS - 6 N2 - In a randomized, double-blind study, 48 women with symptomatic bacterial vaginosis were assigned to receive either 5 g of 2% clindamycin vaginal cream daily or 500 mg metronidazole oral tablets twice a day for 7 days. After completion of therapy, there was no significant difference in cure rates (clindamycin 72% versus metronidazole 87%). One month later, 61% of the patients in each group were still cured. Adverse reactions were mild in both groups. We conclude that clindamycin cream is a safe, well tolerated, and effective alternative to oral metronidazole for treatment of bacterial vaginosis. SN - 0029-7844 UR - https://www.unboundmedicine.com/medline/citation/1579299/Bacterial_vaginosis:_treatment_with_clindamycin_cream_versus_oral_metronidazole_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=1579299.ui DB - PRIME DP - Unbound Medicine ER -