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[Unusual reactions to food additives].
Pediatr Med Chir. 1992 Jan-Feb; 14(1):39-42.PM

Abstract

The most important symptoms caused by food additives are urticaria and angioedema, but rhinitis, asthma and gastrointestinal disturbances are also reported. Only seldom food additives have been shown to induce symptoms in other organs such central nervous system or joints and with a sparse objective evidence. In this study, we report two cases of unusual reactions to food additives (tartrazine and benzoates) involving mainly the central nervous system (headache, migraine, overactivity, concentration and learning difficulties, depression) and joints (arthralgias), confirmed with diet and double blind challenge. The possible pathogenetic mechanisms are also discussed.

Authors+Show Affiliations

Novembre E
Servizio di Allergologia, Clinica Pediatrica 3, Firenze, Italia.
Dini L
No affiliation info available
Bernardini R
No affiliation info available
Resti M
No affiliation info available
Vierucci A
No affiliation info available

MeSH

AdolescentBenzoatesBenzoic AcidCentral Nervous System DiseasesChildDouble-Blind MethodFemaleFood AdditivesFood HypersensitivityHumansJoint DiseasesMaleTartrazine

Pub Type(s)

Case Reports
Clinical Trial
Controlled Clinical Trial
English Abstract
Journal Article

Language

ita

PubMed ID

1579515

Citation

Novembre, E, et al. "[Unusual Reactions to Food Additives]." La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics, vol. 14, no. 1, 1992, pp. 39-42.
Novembre E, Dini L, Bernardini R, et al. [Unusual reactions to food additives]. Pediatr Med Chir. 1992;14(1):39-42.
Novembre, E., Dini, L., Bernardini, R., Resti, M., & Vierucci, A. (1992). [Unusual reactions to food additives]. La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics, 14(1), 39-42.
Novembre E, et al. [Unusual Reactions to Food Additives]. Pediatr Med Chir. 1992 Jan-Feb;14(1):39-42. PubMed PMID: 1579515.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Unusual reactions to food additives]. AU - Novembre,E, AU - Dini,L, AU - Bernardini,R, AU - Resti,M, AU - Vierucci,A, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 39 EP - 42 JF - La Pediatria medica e chirurgica : Medical and surgical pediatrics JO - Pediatr Med Chir VL - 14 IS - 1 N2 - The most important symptoms caused by food additives are urticaria and angioedema, but rhinitis, asthma and gastrointestinal disturbances are also reported. Only seldom food additives have been shown to induce symptoms in other organs such central nervous system or joints and with a sparse objective evidence. In this study, we report two cases of unusual reactions to food additives (tartrazine and benzoates) involving mainly the central nervous system (headache, migraine, overactivity, concentration and learning difficulties, depression) and joints (arthralgias), confirmed with diet and double blind challenge. The possible pathogenetic mechanisms are also discussed. SN - 0391-5387 UR - https://www.unboundmedicine.com/medline/citation/1579515/[Unusual_reactions_to_food_additives]_ L2 - https://medlineplus.gov/jointdisorders.html DB - PRIME DP - Unbound Medicine ER -