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Evaluation of antioxidant potential of the cultured mycobiont of a lichen Usnea ghattensis.
Phytother Res. 2005 Jan; 19(1):58-64.PR

Abstract

The biologically active compounds, antioxidant activities and free radical scavenging effects of dry matter of cultural medium (DMCM), filtrate (DMF) and different solvent extracts of mycobiont from lichen species Usnea ghattensis in submerged culture (UGSC) were investigated. DMF showed the strongest inhibition of lipid peroxidation as a function of its concentration, and was comparable to the antioxidant activity of BHA at the same concentration of 0.2 mg/mL. The hexane extract of mycobiont had the weakest antioxidant ability, whereas other mycobiont extracts exhibited a modest to strong inhibition of lipid peroxidation and in free radical scavenging activity. The antioxidant activities of mycobiont extracts were correlated with the presence of total polyphenol content in the extract. It was found that antioxidant components in methanol, acetone, ethanol and hexane extracts must be derived from the secondary metabolites produced by the lichen mycobiont. The results presented herein indicate that extracts of cultured mycobiont of lichen Usnea ghattensis could possibly act as chemopreventing agent with respect to free radical-related diseases.

Authors+Show Affiliations

Agharkar Research Institute, G. G. Agarkar Road, Pune-411 004, India. Bcbehera2002@yahoo.co.inNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15799000

Citation

Behera, B C., et al. "Evaluation of Antioxidant Potential of the Cultured Mycobiont of a Lichen Usnea Ghattensis." Phytotherapy Research : PTR, vol. 19, no. 1, 2005, pp. 58-64.
Behera BC, Verma N, Sonone A, et al. Evaluation of antioxidant potential of the cultured mycobiont of a lichen Usnea ghattensis. Phytother Res. 2005;19(1):58-64.
Behera, B. C., Verma, N., Sonone, A., & Makhija, U. (2005). Evaluation of antioxidant potential of the cultured mycobiont of a lichen Usnea ghattensis. Phytotherapy Research : PTR, 19(1), 58-64.
Behera BC, et al. Evaluation of Antioxidant Potential of the Cultured Mycobiont of a Lichen Usnea Ghattensis. Phytother Res. 2005;19(1):58-64. PubMed PMID: 15799000.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of antioxidant potential of the cultured mycobiont of a lichen Usnea ghattensis. AU - Behera,B C, AU - Verma,Neeraj, AU - Sonone,Anjali, AU - Makhija,Urmila, PY - 2005/3/31/pubmed PY - 2005/5/20/medline PY - 2005/3/31/entrez SP - 58 EP - 64 JF - Phytotherapy research : PTR JO - Phytother Res VL - 19 IS - 1 N2 - The biologically active compounds, antioxidant activities and free radical scavenging effects of dry matter of cultural medium (DMCM), filtrate (DMF) and different solvent extracts of mycobiont from lichen species Usnea ghattensis in submerged culture (UGSC) were investigated. DMF showed the strongest inhibition of lipid peroxidation as a function of its concentration, and was comparable to the antioxidant activity of BHA at the same concentration of 0.2 mg/mL. The hexane extract of mycobiont had the weakest antioxidant ability, whereas other mycobiont extracts exhibited a modest to strong inhibition of lipid peroxidation and in free radical scavenging activity. The antioxidant activities of mycobiont extracts were correlated with the presence of total polyphenol content in the extract. It was found that antioxidant components in methanol, acetone, ethanol and hexane extracts must be derived from the secondary metabolites produced by the lichen mycobiont. The results presented herein indicate that extracts of cultured mycobiont of lichen Usnea ghattensis could possibly act as chemopreventing agent with respect to free radical-related diseases. SN - 0951-418X UR - https://www.unboundmedicine.com/medline/citation/15799000/Evaluation_of_antioxidant_potential_of_the_cultured_mycobiont_of_a_lichen_Usnea_ghattensis_ L2 - https://doi.org/10.1002/ptr.1607 DB - PRIME DP - Unbound Medicine ER -