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Influence of Casearia esculenta root extract on glycoprotein components in streptozotocin diabetic rats.
Pharmazie. 2005 Mar; 60(3):229-32.P

Abstract

The present study was aimed to evaluate the role of the indigenous antidiabetic medicinal plant Casearia esculenta on glycoprotein components in streptozotocin-induced diabetic rats in plasma, liver, kidney and cardiac tissues. Streptozotocin injection (50 mg/kg body weight) caused massive elevation of glycoprotein components such as hexose, hexosamine, sialic acid and fucose in plasma and tissues of diabetic control and experimental animals. Oral administration of C. esculenta root extract (200 and 300 mg/kg body weight) for 45 days significantly reverted the hexose, hexosamine, sialic acid and fucose levels to near normal values. These results suggest a normalizing effect of C. esculenta on glycoprotein components in STZ diabetic rats.

Authors+Show Affiliations

Department of Biochemistry, Faculty of Science, Rajah Muthiah Medical College and Hospital, Annamalai University, Annamalainagar, Tamilnadu, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15801680

Citation

Prakasam, A, et al. "Influence of Casearia Esculenta Root Extract On Glycoprotein Components in Streptozotocin Diabetic Rats." Die Pharmazie, vol. 60, no. 3, 2005, pp. 229-32.
Prakasam A, Sethupathy S, Pugalendi KV. Influence of Casearia esculenta root extract on glycoprotein components in streptozotocin diabetic rats. Pharmazie. 2005;60(3):229-32.
Prakasam, A., Sethupathy, S., & Pugalendi, K. V. (2005). Influence of Casearia esculenta root extract on glycoprotein components in streptozotocin diabetic rats. Die Pharmazie, 60(3), 229-32.
Prakasam A, Sethupathy S, Pugalendi KV. Influence of Casearia Esculenta Root Extract On Glycoprotein Components in Streptozotocin Diabetic Rats. Pharmazie. 2005;60(3):229-32. PubMed PMID: 15801680.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of Casearia esculenta root extract on glycoprotein components in streptozotocin diabetic rats. AU - Prakasam,A, AU - Sethupathy,S, AU - Pugalendi,K V, PY - 2005/4/2/pubmed PY - 2005/4/29/medline PY - 2005/4/2/entrez SP - 229 EP - 32 JF - Die Pharmazie JO - Pharmazie VL - 60 IS - 3 N2 - The present study was aimed to evaluate the role of the indigenous antidiabetic medicinal plant Casearia esculenta on glycoprotein components in streptozotocin-induced diabetic rats in plasma, liver, kidney and cardiac tissues. Streptozotocin injection (50 mg/kg body weight) caused massive elevation of glycoprotein components such as hexose, hexosamine, sialic acid and fucose in plasma and tissues of diabetic control and experimental animals. Oral administration of C. esculenta root extract (200 and 300 mg/kg body weight) for 45 days significantly reverted the hexose, hexosamine, sialic acid and fucose levels to near normal values. These results suggest a normalizing effect of C. esculenta on glycoprotein components in STZ diabetic rats. SN - 0031-7144 UR - https://www.unboundmedicine.com/medline/citation/15801680/Influence_of_Casearia_esculenta_root_extract_on_glycoprotein_components_in_streptozotocin_diabetic_rats_ DB - PRIME DP - Unbound Medicine ER -