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Resting energy expenditure in Duchenne patients using home mechanical ventilation.
Eur Respir J. 2005 Apr; 25(4):682-7.ER

Abstract

Nutritional status is both important and difficult to assess in patients with Duchenne muscular dystrophy (DMD), particularly in those requiring mechanical ventilation (MV). The current authors evaluated body composition (bio-impedancemetry), resting energy expenditure (REE; indirect calorimetry) and energy intake in 20 adult patients with DMD using home MV (nocturnal: n = 13; continuous: n = 7) and 12 age-matched healthy controls. The patients were smaller in height than the controls and had a lower body weight. Most of the reduction in body mass index was accounted for by a reduction in fat free mass (FFM). REE (kJ) was significantly reduced in the patients (4559+/-853 kJ x 24 h(-1) versus 7407+/-1312 kJ x 24 h(-1)), but the difference disappeared after correction for FFM. REE and FFM were correlated in both the controls and patients, but less strongly in the latter, the lower strength of the association being due to the patients using continuous MV (REE and FFM uncorrelated). The food intake of the patients was 1.2+/-0.4 greater than their REE. This study shows that patients with advanced forms of Duchenne muscular dystrophy have balanced energy intakes and resting energy expenditure.

Authors+Show Affiliations

Service de Pneumologie et de Réanimation, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83, Bd de l'Hôpital, 75651 Paris Cedex 13, France. jesus.gonzalez@psl.ap-hop-paris.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15802343

Citation

Gonzalez-Bermejo, J, et al. "Resting Energy Expenditure in Duchenne Patients Using Home Mechanical Ventilation." The European Respiratory Journal, vol. 25, no. 4, 2005, pp. 682-7.
Gonzalez-Bermejo J, Lofaso F, Falaize L, et al. Resting energy expenditure in Duchenne patients using home mechanical ventilation. Eur Respir J. 2005;25(4):682-7.
Gonzalez-Bermejo, J., Lofaso, F., Falaize, L., Lejaille, M., Raphaël, J. C., Similowski, T., & Melchior, J. C. (2005). Resting energy expenditure in Duchenne patients using home mechanical ventilation. The European Respiratory Journal, 25(4), 682-7.
Gonzalez-Bermejo J, et al. Resting Energy Expenditure in Duchenne Patients Using Home Mechanical Ventilation. Eur Respir J. 2005;25(4):682-7. PubMed PMID: 15802343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Resting energy expenditure in Duchenne patients using home mechanical ventilation. AU - Gonzalez-Bermejo,J, AU - Lofaso,F, AU - Falaize,L, AU - Lejaille,M, AU - Raphaël,J-C, AU - Similowski,T, AU - Melchior,J-C, PY - 2005/4/2/pubmed PY - 2005/12/24/medline PY - 2005/4/2/entrez SP - 682 EP - 7 JF - The European respiratory journal JO - Eur. Respir. J. VL - 25 IS - 4 N2 - Nutritional status is both important and difficult to assess in patients with Duchenne muscular dystrophy (DMD), particularly in those requiring mechanical ventilation (MV). The current authors evaluated body composition (bio-impedancemetry), resting energy expenditure (REE; indirect calorimetry) and energy intake in 20 adult patients with DMD using home MV (nocturnal: n = 13; continuous: n = 7) and 12 age-matched healthy controls. The patients were smaller in height than the controls and had a lower body weight. Most of the reduction in body mass index was accounted for by a reduction in fat free mass (FFM). REE (kJ) was significantly reduced in the patients (4559+/-853 kJ x 24 h(-1) versus 7407+/-1312 kJ x 24 h(-1)), but the difference disappeared after correction for FFM. REE and FFM were correlated in both the controls and patients, but less strongly in the latter, the lower strength of the association being due to the patients using continuous MV (REE and FFM uncorrelated). The food intake of the patients was 1.2+/-0.4 greater than their REE. This study shows that patients with advanced forms of Duchenne muscular dystrophy have balanced energy intakes and resting energy expenditure. SN - 0903-1936 UR - https://www.unboundmedicine.com/medline/citation/15802343/Resting_energy_expenditure_in_Duchenne_patients_using_home_mechanical_ventilation_ L2 - http://erj.ersjournals.com/cgi/pmidlookup?view=long&pmid=15802343 DB - PRIME DP - Unbound Medicine ER -