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Inter-instrumental variation of skin capacitance measured with the Corneometer.
Skin Res Technol. 2005 May; 11(2):107-9.SR

Abstract

BACKGROUND/PURPOSE

Measurement of skin surface and stratum corneum (SC) hydration during clinical and/or experimental trials needs devices with acceptable reproducibility and sensitivity under conditions ranging from increased and normal to low hydration. A previous study comparing Corneometer instruments (European group for Efficacy Measurement of Cosmetics and Other products--EEMCO) used for measurement of electrical capacitance of skin indicated a major difference among Corneometer instruments. The aim of this study was to assess three inter-instrumental similar Corneometer instruments (two pieces of CM820 and one CM810) in normal skin. We named them CM-A(CM820), CM-B(CM820), and CM-C(CM810).

METHODS

The hydration state of SC measured as electrical capacitance of six body sites were measured in 53 subjects with three Corneometer instruments.

RESULT

We found that the Corneometer instruments displayed close capacitance levels. When one Corneometer was plotted against another the regression line indicated a good correlation among instruments albeit a major and random disagreement could appear in individual sites as an exception.

CONCLUSION

Three Corneometer instruments evaluated in this study gave close measurements and correlated well. Nevertheless, pretest validation of instruments should be undertaken in multicenter studies where capacitance data are compared or pooled, and concordance among instruments should be documented prior to study.

Authors+Show Affiliations

Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark. kenmockjp@yahoo.co.jpNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

15807808

Citation

O'goshi, Ken-Ichiro, and Jørgen Serup. "Inter-instrumental Variation of Skin Capacitance Measured With the Corneometer." Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), vol. 11, no. 2, 2005, pp. 107-9.
O'goshi K, Serup J. Inter-instrumental variation of skin capacitance measured with the Corneometer. Skin Res Technol. 2005;11(2):107-9.
O'goshi, K., & Serup, J. (2005). Inter-instrumental variation of skin capacitance measured with the Corneometer. Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 11(2), 107-9.
O'goshi K, Serup J. Inter-instrumental Variation of Skin Capacitance Measured With the Corneometer. Skin Res Technol. 2005;11(2):107-9. PubMed PMID: 15807808.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Inter-instrumental variation of skin capacitance measured with the Corneometer. AU - O'goshi,Ken-Ichiro, AU - Serup,Jørgen, PY - 2005/4/6/pubmed PY - 2005/7/20/medline PY - 2005/4/6/entrez SP - 107 EP - 9 JF - Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) JO - Skin Res Technol VL - 11 IS - 2 N2 - BACKGROUND/PURPOSE: Measurement of skin surface and stratum corneum (SC) hydration during clinical and/or experimental trials needs devices with acceptable reproducibility and sensitivity under conditions ranging from increased and normal to low hydration. A previous study comparing Corneometer instruments (European group for Efficacy Measurement of Cosmetics and Other products--EEMCO) used for measurement of electrical capacitance of skin indicated a major difference among Corneometer instruments. The aim of this study was to assess three inter-instrumental similar Corneometer instruments (two pieces of CM820 and one CM810) in normal skin. We named them CM-A(CM820), CM-B(CM820), and CM-C(CM810). METHODS: The hydration state of SC measured as electrical capacitance of six body sites were measured in 53 subjects with three Corneometer instruments. RESULT: We found that the Corneometer instruments displayed close capacitance levels. When one Corneometer was plotted against another the regression line indicated a good correlation among instruments albeit a major and random disagreement could appear in individual sites as an exception. CONCLUSION: Three Corneometer instruments evaluated in this study gave close measurements and correlated well. Nevertheless, pretest validation of instruments should be undertaken in multicenter studies where capacitance data are compared or pooled, and concordance among instruments should be documented prior to study. SN - 0909-752X UR - https://www.unboundmedicine.com/medline/citation/15807808/Inter_instrumental_variation_of_skin_capacitance_measured_with_the_Corneometer_ L2 - https://doi.org/10.1111/j.1600-0846.2005.00086.x DB - PRIME DP - Unbound Medicine ER -