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Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus.
Z Naturforsch C J Biosci. 2004 Jul-Aug; 59(7-8):481-4.ZN

Abstract

In vitro antioxidant activities of three sweet dihydrochalcone glucosides from the leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae), trilobatin 2"-acetate (1), phloridzin (2) and trilobatin (3), were investigated. The IC50 (50% inhibitory concentration) values for compounds 1-3 of lipid peroxidation in rat liver homogenate were 261, 28, 88 microM, respectively. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC50 (50% effective concentration) values of 575, 167, 128 microM, and glutathione peroxidase (GSH-Px) activity with EC50 values of 717, 347, 129 microM, respectively, and showed only weak DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity.

Authors+Show Affiliations

Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming 650204, P R China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15813365

Citation

Yang, Wei-Min, et al. "Antioxidant Activities of Three Dihydrochalcone Glucosides From Leaves of Lithocarpus Pachyphyllus." Zeitschrift Fur Naturforschung. C, Journal of Biosciences, vol. 59, no. 7-8, 2004, pp. 481-4.
Yang WM, Liu JK, Qin XD, et al. Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. Z Naturforsch C J Biosci. 2004;59(7-8):481-4.
Yang, W. M., Liu, J. K., Qin, X. D., Wu, W. L., & Chen, Z. H. (2004). Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. Zeitschrift Fur Naturforschung. C, Journal of Biosciences, 59(7-8), 481-4.
Yang WM, et al. Antioxidant Activities of Three Dihydrochalcone Glucosides From Leaves of Lithocarpus Pachyphyllus. Z Naturforsch C J Biosci. 2004 Jul-Aug;59(7-8):481-4. PubMed PMID: 15813365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus. AU - Yang,Wei-Min, AU - Liu,Ji-Kai, AU - Qin,Xiang-Dong, AU - Wu,Wan-Lin, AU - Chen,Zhi-He, PY - 2005/4/9/pubmed PY - 2005/6/29/medline PY - 2005/4/9/entrez SP - 481 EP - 4 JF - Zeitschrift fur Naturforschung. C, Journal of biosciences JO - Z Naturforsch C J Biosci VL - 59 IS - 7-8 N2 - In vitro antioxidant activities of three sweet dihydrochalcone glucosides from the leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae), trilobatin 2"-acetate (1), phloridzin (2) and trilobatin (3), were investigated. The IC50 (50% inhibitory concentration) values for compounds 1-3 of lipid peroxidation in rat liver homogenate were 261, 28, 88 microM, respectively. Compounds 1-3 increased superoxide dismutase (SOD) activity with EC50 (50% effective concentration) values of 575, 167, 128 microM, and glutathione peroxidase (GSH-Px) activity with EC50 values of 717, 347, 129 microM, respectively, and showed only weak DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity. SN - 0939-5075 UR - https://www.unboundmedicine.com/medline/citation/15813365/Antioxidant_activities_of_three_dihydrochalcone_glucosides_from_leaves_of_Lithocarpus_pachyphyllus_ L2 - https://www.degruyter.com/document/doi/10.1515/znc-2004-7-805 DB - PRIME DP - Unbound Medicine ER -