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Predictors of controlled ambulatory blood pressure in treated hypertensive patients with uncontrolled office blood pressure.
Hypertens Res 2004; 27(11):805-11HR

Abstract

Although some treated hypertensive patients have controlled 24-h ambulatory blood pressure (ABP) despite their uncontrolled office blood pressure (BP), the factors relating to the control of 24-h ABP remain unknown. We conducted a study to assess 24-h ABP and its association with other cardiovascular risk factors, including echocardiographic left ventricular hypertrophy (LVH), in elderly hypertensive patients (n =41) with uncontrolled office BP (>140/90 mmHg) during long-term medication. Although a majority of the patients had isolated elevation of office systolic BP (SBP), there was no significant relationship between office SBP and 24-h SBP, and about half of the patients had controlled 24-h ABP (125+/-8/69+/-6 mmHg). Patients with controlled 24-h ABP (125+/-8/69+/-6 mmHg) had similar office BP (150+/-6/77+/-5 vs. 150+/-7/79+/-7 mmHg), but lower left ventricular mass index (LVMI) (123+/-34 vs. 156+/-34 g/m(2)) and body mass index (BMI) (24.4+/-2.1 vs. 26.4+/-3.6 kg/m(2)) compared with those with uncontrolled 24-h ABP (149+/-13/78+/-7 mmHg). Multivariate analysis showed that LVMI and BMI were independently associated with controlled 24-h ABP, and the control status of 24-h ABP was highly dependent on the presence of LVH and obesity. Therefore, absence of LVH and obesity may be useful for predicting the level of control of 24-h ABP in treated patients whose office BP is uncontrolled without ABP measurements.

Authors+Show Affiliations

Otsuki Hospital, Kochi, Japan. hoken2@mb.gallery.ne.jpNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15824462

Citation

Ono, Ayumu, and Toshiro Fujita. "Predictors of Controlled Ambulatory Blood Pressure in Treated Hypertensive Patients With Uncontrolled Office Blood Pressure." Hypertension Research : Official Journal of the Japanese Society of Hypertension, vol. 27, no. 11, 2004, pp. 805-11.
Ono A, Fujita T. Predictors of controlled ambulatory blood pressure in treated hypertensive patients with uncontrolled office blood pressure. Hypertens Res. 2004;27(11):805-11.
Ono, A., & Fujita, T. (2004). Predictors of controlled ambulatory blood pressure in treated hypertensive patients with uncontrolled office blood pressure. Hypertension Research : Official Journal of the Japanese Society of Hypertension, 27(11), pp. 805-11.
Ono A, Fujita T. Predictors of Controlled Ambulatory Blood Pressure in Treated Hypertensive Patients With Uncontrolled Office Blood Pressure. Hypertens Res. 2004;27(11):805-11. PubMed PMID: 15824462.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Predictors of controlled ambulatory blood pressure in treated hypertensive patients with uncontrolled office blood pressure. AU - Ono,Ayumu, AU - Fujita,Toshiro, PY - 2005/4/13/pubmed PY - 2005/7/16/medline PY - 2005/4/13/entrez SP - 805 EP - 11 JF - Hypertension research : official journal of the Japanese Society of Hypertension JO - Hypertens. Res. VL - 27 IS - 11 N2 - Although some treated hypertensive patients have controlled 24-h ambulatory blood pressure (ABP) despite their uncontrolled office blood pressure (BP), the factors relating to the control of 24-h ABP remain unknown. We conducted a study to assess 24-h ABP and its association with other cardiovascular risk factors, including echocardiographic left ventricular hypertrophy (LVH), in elderly hypertensive patients (n =41) with uncontrolled office BP (>140/90 mmHg) during long-term medication. Although a majority of the patients had isolated elevation of office systolic BP (SBP), there was no significant relationship between office SBP and 24-h SBP, and about half of the patients had controlled 24-h ABP (125+/-8/69+/-6 mmHg). Patients with controlled 24-h ABP (125+/-8/69+/-6 mmHg) had similar office BP (150+/-6/77+/-5 vs. 150+/-7/79+/-7 mmHg), but lower left ventricular mass index (LVMI) (123+/-34 vs. 156+/-34 g/m(2)) and body mass index (BMI) (24.4+/-2.1 vs. 26.4+/-3.6 kg/m(2)) compared with those with uncontrolled 24-h ABP (149+/-13/78+/-7 mmHg). Multivariate analysis showed that LVMI and BMI were independently associated with controlled 24-h ABP, and the control status of 24-h ABP was highly dependent on the presence of LVH and obesity. Therefore, absence of LVH and obesity may be useful for predicting the level of control of 24-h ABP in treated patients whose office BP is uncontrolled without ABP measurements. SN - 0916-9636 UR - https://www.unboundmedicine.com/medline/citation/15824462/Predictors_of_controlled_ambulatory_blood_pressure_in_treated_hypertensive_patients_with_uncontrolled_office_blood_pressure_ L2 - http://joi.jlc.jst.go.jp/JST.JSTAGE/hypres/27.805?from=PubMed DB - PRIME DP - Unbound Medicine ER -