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Diagnosis of gastroesophageal reflux disease using a new questionnaire.
J Gastroenterol Hepatol. 2005 Apr; 20(4):643-7.JG

Abstract

BACKGROUND AND AIM

An early and accurate evaluation by a general practitioner is needed to screen out non-gastroesophageal reflux disease (GERD) patients. A recent questionnaire (QUEST) highlighted problems with specificity and complexity, so the aim of the present study was to design a simplified questionnaire.

METHODS

When admitted to hospital to undergo an upper gastrointestinal endoscopy for suspected GERD, 333 patients completed a 50-item questionnaire requiring 'yes/no' answers to different combinations of questions relating to symptoms of upper gastrointestinal tract conditions (e.g. GERD, ulcers and functional dyspepsia) and psychosomatic symptoms. The endoscopic diagnosis was then correlated with the rate of positive answers to each question.

RESULTS

Based on the analysis of the 50 items, the 8-10 questions most often answered affirmatively by each of the GERD and non-GERD groups were chosen for the simplified questionnaire. Three draft questionnaires were compiled. After calculating the sensitivity, specificity and accuracy in relation to the diagnosis of GERD and other conditions, it was found that questionnaire B (selection of persons answering 'yes' to at least one of questions 1-5 and exclusion of persons answering 'yes' to at least three of questions 7-10) had a high sensitivity, high specificity and low false positive rate.

CONCLUSION

A novel questionnaire was developed. It was designed to detect the symptoms of GERD while simultaneously excluding non-GERD patients. This simplified nine-item simplified questionnaire had a sensitivity of 79.8%, a specificity of 53.6% and an accuracy of 63.4%.

Authors+Show Affiliations

Department of Endoscopy and Endoscopic Surgery, Gunma University Hospital, Gunma, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15836717

Citation

Shimoyama, Yasuyuki, et al. "Diagnosis of Gastroesophageal Reflux Disease Using a New Questionnaire." Journal of Gastroenterology and Hepatology, vol. 20, no. 4, 2005, pp. 643-7.
Shimoyama Y, Kusano M, Sugimoto S, et al. Diagnosis of gastroesophageal reflux disease using a new questionnaire. J Gastroenterol Hepatol. 2005;20(4):643-7.
Shimoyama, Y., Kusano, M., Sugimoto, S., Kawamura, O., Maeda, M., Minashi, K., Kuribayashi, S., Higuchi, T., Zai, H., Ino, K., Horikoshi, T., Moki, F., Sugiyama, T., Toki, M., Ohwada, T., & Mori, M. (2005). Diagnosis of gastroesophageal reflux disease using a new questionnaire. Journal of Gastroenterology and Hepatology, 20(4), 643-7.
Shimoyama Y, et al. Diagnosis of Gastroesophageal Reflux Disease Using a New Questionnaire. J Gastroenterol Hepatol. 2005;20(4):643-7. PubMed PMID: 15836717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis of gastroesophageal reflux disease using a new questionnaire. AU - Shimoyama,Yasuyuki, AU - Kusano,Motoyasu, AU - Sugimoto,Sayaka, AU - Kawamura,Osamu, AU - Maeda,Masaki, AU - Minashi,Keiko, AU - Kuribayashi,Shikou, AU - Higuchi,Tatsuya, AU - Zai,Hiroaki, AU - Ino,Kyoko, AU - Horikoshi,Tsutomu, AU - Moki,Fumitaka, AU - Sugiyama,Tadashi, AU - Toki,Munetoshi, AU - Ohwada,Tsuneo, AU - Mori,Masatomo, PY - 2005/4/20/pubmed PY - 2005/8/3/medline PY - 2005/4/20/entrez SP - 643 EP - 7 JF - Journal of gastroenterology and hepatology JO - J. Gastroenterol. Hepatol. VL - 20 IS - 4 N2 - BACKGROUND AND AIM: An early and accurate evaluation by a general practitioner is needed to screen out non-gastroesophageal reflux disease (GERD) patients. A recent questionnaire (QUEST) highlighted problems with specificity and complexity, so the aim of the present study was to design a simplified questionnaire. METHODS: When admitted to hospital to undergo an upper gastrointestinal endoscopy for suspected GERD, 333 patients completed a 50-item questionnaire requiring 'yes/no' answers to different combinations of questions relating to symptoms of upper gastrointestinal tract conditions (e.g. GERD, ulcers and functional dyspepsia) and psychosomatic symptoms. The endoscopic diagnosis was then correlated with the rate of positive answers to each question. RESULTS: Based on the analysis of the 50 items, the 8-10 questions most often answered affirmatively by each of the GERD and non-GERD groups were chosen for the simplified questionnaire. Three draft questionnaires were compiled. After calculating the sensitivity, specificity and accuracy in relation to the diagnosis of GERD and other conditions, it was found that questionnaire B (selection of persons answering 'yes' to at least one of questions 1-5 and exclusion of persons answering 'yes' to at least three of questions 7-10) had a high sensitivity, high specificity and low false positive rate. CONCLUSION: A novel questionnaire was developed. It was designed to detect the symptoms of GERD while simultaneously excluding non-GERD patients. This simplified nine-item simplified questionnaire had a sensitivity of 79.8%, a specificity of 53.6% and an accuracy of 63.4%. SN - 0815-9319 UR - https://www.unboundmedicine.com/medline/citation/15836717/Diagnosis_of_gastroesophageal_reflux_disease_using_a_new_questionnaire_ L2 - https://doi.org/10.1111/j.1440-1746.2005.03776.x DB - PRIME DP - Unbound Medicine ER -