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Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay.
J Bacteriol. 2005 May; 187(9):3282-6.JB

Abstract

Transcription of the Escherichia coli osmB gene is induced by several stress conditions. osmB is expressed from two promoters, osmBp1 and osmBp2. The downstream promoter, osmBp2, is induced after osmotic shock or upon entry into stationary phase in a sigma(S)-dependent manner. The upstream promoter, osmBp1, is independent of sigma(S) and is activated by RcsB, the response regulator of the His-Asp phosphorelay signal transduction system RcsCDB. RcsB is responsible for the induction of osmBp1 following treatment with chlorpromazine. Activation of osmBp1 by RcsB requires a sequence upstream of its -35 element similar to the RcsB binding site consensus, suggesting a direct regulatory role. osmB appears as another example of a multistress-responsive gene whose transcription involves both a sigma(S)-dependent promoter and a second one independent of sigma(S) but controlled by stress-specific transcription factors.

Authors+Show Affiliations

Laboratoire de Microbiologie et Génétique Moléculaires, UMR5100 Centre National de la Recherche Scientifique-Université Toulouse III, 118 Route de Narbonne, 31062 Toulouse, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15838058

Citation

Boulanger, Alice, et al. "Multistress Regulation in Escherichia Coli: Expression of osmB Involves Two Independent Promoters Responding Either to sigmaS or to the RcsCDB His-Asp Phosphorelay." Journal of Bacteriology, vol. 187, no. 9, 2005, pp. 3282-6.
Boulanger A, Francez-Charlot A, Conter A, et al. Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay. J Bacteriol. 2005;187(9):3282-6.
Boulanger, A., Francez-Charlot, A., Conter, A., Castanié-Cornet, M. P., Cam, K., & Gutierrez, C. (2005). Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay. Journal of Bacteriology, 187(9), 3282-6.
Boulanger A, et al. Multistress Regulation in Escherichia Coli: Expression of osmB Involves Two Independent Promoters Responding Either to sigmaS or to the RcsCDB His-Asp Phosphorelay. J Bacteriol. 2005;187(9):3282-6. PubMed PMID: 15838058.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay. AU - Boulanger,Alice, AU - Francez-Charlot,Anne, AU - Conter,Annie, AU - Castanié-Cornet,Marie-Pierre, AU - Cam,Kaymeuang, AU - Gutierrez,Claude, PY - 2005/4/20/pubmed PY - 2005/6/23/medline PY - 2005/4/20/entrez SP - 3282 EP - 6 JF - Journal of bacteriology JO - J Bacteriol VL - 187 IS - 9 N2 - Transcription of the Escherichia coli osmB gene is induced by several stress conditions. osmB is expressed from two promoters, osmBp1 and osmBp2. The downstream promoter, osmBp2, is induced after osmotic shock or upon entry into stationary phase in a sigma(S)-dependent manner. The upstream promoter, osmBp1, is independent of sigma(S) and is activated by RcsB, the response regulator of the His-Asp phosphorelay signal transduction system RcsCDB. RcsB is responsible for the induction of osmBp1 following treatment with chlorpromazine. Activation of osmBp1 by RcsB requires a sequence upstream of its -35 element similar to the RcsB binding site consensus, suggesting a direct regulatory role. osmB appears as another example of a multistress-responsive gene whose transcription involves both a sigma(S)-dependent promoter and a second one independent of sigma(S) but controlled by stress-specific transcription factors. SN - 0021-9193 UR - https://www.unboundmedicine.com/medline/citation/15838058/Multistress_regulation_in_Escherichia_coli:_expression_of_osmB_involves_two_independent_promoters_responding_either_to_sigmaS_or_to_the_RcsCDB_His_Asp_phosphorelay_ L2 - https://journals.asm.org/doi/10.1128/JB.187.9.3282-3286.2005?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -