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[Comparison of a T1-weighted inversion-recovery-, gradient-echo- and spin-echo sequence for imaging of the brain at 3.0 Tesla].
Rofo. 2005 Apr; 177(4):536-42.ROFO

Abstract

PURPOSE

The increased T1 relaxation times at 3.0 Tesla lead to a reduced T1 contrast, requiring adaptation of imaging protocols for high magnetic fields. This prospective study assesses the performance of three techniques for T1-weighted imaging (T1w) at 3.0 T with regard to gray-white differentiation and contrast-to-noise-ratio (CNR).

MATERIALS AND METHODS

Thirty-one patients were examined at a 3.0 T system with axial T1 w inversion recovery (IR), spin-echo (SE) and gradient echo (GE) sequences and after contrast enhancement (CE) with CE-SE and CE-GE sequences. For qualitative analysis, the images were ranked with regard to artifacts, gray-white differentiation, image noise and overall diagnostic quality. For quantitative analysis, the CNR was calculated, and cortex and basal ganglia were compared with the white matter.

RESULTS

In the qualitative analysis, IR was judged superior to SE and GE for gray-white differentiation, image noise and overall diagnostic quality, but inferior to the GE sequence with regard to artifacts. CE-GE proved superior to CE-SE in all categories. In the quantitative analysis, CNR of the basal ganglia was highest for IR, followed by GE and SE. For the CNR of the cortex, no significant difference was found between IR (16.9) and GE (15.4) but both were superior to the SE (9.4). The CNR of the cortex was significantly higher for CE-GE compared to CE-SE (12.7 vs. 7.6, p < 0.001), but the CNR of the basal ganglia was not significantly different.

CONCLUSION

For unenhanced T1 w imaging at 3.0 T, the IR technique is, despite increased artifacts, the method of choice due to its superior gray-white differentiation and best overall image quality. For CE-studies, GE sequences are recommended. For cerebral imaging, SE sequences give unsatisfactory results at 3.0 T.

Authors+Show Affiliations

Institut für Klinische Radiologie, Universitätsklinikum Münster. cstehling@uni-muenster.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Controlled Clinical Trial
English Abstract
Journal Article

Language

ger

PubMed ID

15838759

Citation

Stehling, C, et al. "[Comparison of a T1-weighted Inversion-recovery-, Gradient-echo- and Spin-echo Sequence for Imaging of the Brain at 3.0 Tesla]." RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, vol. 177, no. 4, 2005, pp. 536-42.
Stehling C, Niederstadt T, Krämer S, et al. [Comparison of a T1-weighted inversion-recovery-, gradient-echo- and spin-echo sequence for imaging of the brain at 3.0 Tesla]. Rofo. 2005;177(4):536-42.
Stehling, C., Niederstadt, T., Krämer, S., Kugel, H., Schwindt, W., Heindel, W., & Bachmann, R. (2005). [Comparison of a T1-weighted inversion-recovery-, gradient-echo- and spin-echo sequence for imaging of the brain at 3.0 Tesla]. RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, 177(4), 536-42.
Stehling C, et al. [Comparison of a T1-weighted Inversion-recovery-, Gradient-echo- and Spin-echo Sequence for Imaging of the Brain at 3.0 Tesla]. Rofo. 2005;177(4):536-42. PubMed PMID: 15838759.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Comparison of a T1-weighted inversion-recovery-, gradient-echo- and spin-echo sequence for imaging of the brain at 3.0 Tesla]. AU - Stehling,C, AU - Niederstadt,T, AU - Krämer,S, AU - Kugel,H, AU - Schwindt,W, AU - Heindel,W, AU - Bachmann,R, PY - 2005/4/20/pubmed PY - 2005/5/20/medline PY - 2005/4/20/entrez SP - 536 EP - 42 JF - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin JO - Rofo VL - 177 IS - 4 N2 - PURPOSE: The increased T1 relaxation times at 3.0 Tesla lead to a reduced T1 contrast, requiring adaptation of imaging protocols for high magnetic fields. This prospective study assesses the performance of three techniques for T1-weighted imaging (T1w) at 3.0 T with regard to gray-white differentiation and contrast-to-noise-ratio (CNR). MATERIALS AND METHODS: Thirty-one patients were examined at a 3.0 T system with axial T1 w inversion recovery (IR), spin-echo (SE) and gradient echo (GE) sequences and after contrast enhancement (CE) with CE-SE and CE-GE sequences. For qualitative analysis, the images were ranked with regard to artifacts, gray-white differentiation, image noise and overall diagnostic quality. For quantitative analysis, the CNR was calculated, and cortex and basal ganglia were compared with the white matter. RESULTS: In the qualitative analysis, IR was judged superior to SE and GE for gray-white differentiation, image noise and overall diagnostic quality, but inferior to the GE sequence with regard to artifacts. CE-GE proved superior to CE-SE in all categories. In the quantitative analysis, CNR of the basal ganglia was highest for IR, followed by GE and SE. For the CNR of the cortex, no significant difference was found between IR (16.9) and GE (15.4) but both were superior to the SE (9.4). The CNR of the cortex was significantly higher for CE-GE compared to CE-SE (12.7 vs. 7.6, p < 0.001), but the CNR of the basal ganglia was not significantly different. CONCLUSION: For unenhanced T1 w imaging at 3.0 T, the IR technique is, despite increased artifacts, the method of choice due to its superior gray-white differentiation and best overall image quality. For CE-studies, GE sequences are recommended. For cerebral imaging, SE sequences give unsatisfactory results at 3.0 T. SN - 1438-9029 UR - https://www.unboundmedicine.com/medline/citation/15838759/[Comparison_of_a_T1_weighted_inversion_recovery__gradient_echo__and_spin_echo_sequence_for_imaging_of_the_brain_at_3_0_Tesla]_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2005-857902 DB - PRIME DP - Unbound Medicine ER -