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[Clinical analysis of benign pelvic mass with high serum levels of CA(125)].
Zhonghua Fu Chan Ke Za Zhi. 2005 Mar; 40(3):178-82.ZF

Abstract

OBJECTIVE

To investigate serum CA(125) levels and the value of serum CA(125) in differential diagnosis of benign pelvic mass.

METHODS

We retrospectively analyzed 492 patients with benign pelvic mass, including 237 cases of benign ovarian tumor and 255 other benign gynecological diseases. Sixty cases of ovarian epithelial cancer were randomly chosen as control group.

RESULTS

The median of serum CA(125) in patients with pelvic tuberculosis, uterine adenomyosis, ovarian endometriosis and ovarian fibroma were all higher than the cut-off level of CA(125) (35 kU/L), being 465.0, 88.9, 59.0 and 44.5 kU/L, respectively. Those of ovarian epithelial cancer patients were significantly higher than in benign pelvic mass (P < 0.01). The highest value of CA(125) among all the benign cases was 1281.0 kU/L, which was seen in a case of ovarian thecoma. The highest median value was 465.0 kU/L, detected in a patient with pelvic tuberculosis.

CONCLUSIONS

Serum CA(125) levels in some benign pelvic mass are higher than the cut-off level of CA(125), such as pelvic tuberculosis, uterine adenomyosis, ovarian fibroma and ovarian endometriosis. The medians of serum CA(125) in benign pelvic mass are much lower than in ovarian epithelial cancer. Serum CA(125) is of significance in the differential diagnosis between hysteromyoma and uterine adenomyosis.

Authors+Show Affiliations

Department of Gynecologic Oncology, Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

15840313

Citation

Zhang, Xin, et al. "[Clinical Analysis of Benign Pelvic Mass With High Serum Levels of CA(125)]." Zhonghua Fu Chan Ke Za Zhi, vol. 40, no. 3, 2005, pp. 178-82.
Zhang X, Wu LY, Li XJ, et al. [Clinical analysis of benign pelvic mass with high serum levels of CA(125)]. Zhonghua Fu Chan Ke Za Zhi. 2005;40(3):178-82.
Zhang, X., Wu, L. Y., Li, X. J., Li, H. J., Zhang, R., & Liu, L. Y. (2005). [Clinical analysis of benign pelvic mass with high serum levels of CA(125)]. Zhonghua Fu Chan Ke Za Zhi, 40(3), 178-82.
Zhang X, et al. [Clinical Analysis of Benign Pelvic Mass With High Serum Levels of CA(125)]. Zhonghua Fu Chan Ke Za Zhi. 2005;40(3):178-82. PubMed PMID: 15840313.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical analysis of benign pelvic mass with high serum levels of CA(125)]. AU - Zhang,Xin, AU - Wu,Ling-ying, AU - Li,Xiao-jiang, AU - Li,Hong-jun, AU - Zhang,Rong, AU - Liu,Li-ying, PY - 2005/4/21/pubmed PY - 2010/6/16/medline PY - 2005/4/21/entrez SP - 178 EP - 82 JF - Zhonghua fu chan ke za zhi JO - Zhonghua Fu Chan Ke Za Zhi VL - 40 IS - 3 N2 - OBJECTIVE: To investigate serum CA(125) levels and the value of serum CA(125) in differential diagnosis of benign pelvic mass. METHODS: We retrospectively analyzed 492 patients with benign pelvic mass, including 237 cases of benign ovarian tumor and 255 other benign gynecological diseases. Sixty cases of ovarian epithelial cancer were randomly chosen as control group. RESULTS: The median of serum CA(125) in patients with pelvic tuberculosis, uterine adenomyosis, ovarian endometriosis and ovarian fibroma were all higher than the cut-off level of CA(125) (35 kU/L), being 465.0, 88.9, 59.0 and 44.5 kU/L, respectively. Those of ovarian epithelial cancer patients were significantly higher than in benign pelvic mass (P < 0.01). The highest value of CA(125) among all the benign cases was 1281.0 kU/L, which was seen in a case of ovarian thecoma. The highest median value was 465.0 kU/L, detected in a patient with pelvic tuberculosis. CONCLUSIONS: Serum CA(125) levels in some benign pelvic mass are higher than the cut-off level of CA(125), such as pelvic tuberculosis, uterine adenomyosis, ovarian fibroma and ovarian endometriosis. The medians of serum CA(125) in benign pelvic mass are much lower than in ovarian epithelial cancer. Serum CA(125) is of significance in the differential diagnosis between hysteromyoma and uterine adenomyosis. SN - 0529-567X UR - https://www.unboundmedicine.com/medline/citation/15840313/[Clinical_analysis_of_benign_pelvic_mass_with_high_serum_levels_of_CA_125_]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0529-567X&amp;year=2005&amp;vol=40&amp;issue=3&amp;fpage=178 DB - PRIME DP - Unbound Medicine ER -