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Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area.
Mov Disord 1992; 7(2):149-52MD

Abstract

Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex-matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p less than 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future case-control studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed.

Authors+Show Affiliations

Department of Neurology, Hospital General Gregorio Marañón, Madrid, Spain.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1584237

Citation

Jiménez-Jiménez, F J., et al. "Exposure to Well Water and Pesticides in Parkinson's Disease: a Case-control Study in the Madrid Area." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 7, no. 2, 1992, pp. 149-52.
Jiménez-Jiménez FJ, Mateo D, Giménez-Roldán S. Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area. Mov Disord. 1992;7(2):149-52.
Jiménez-Jiménez, F. J., Mateo, D., & Giménez-Roldán, S. (1992). Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area. Movement Disorders : Official Journal of the Movement Disorder Society, 7(2), pp. 149-52.
Jiménez-Jiménez FJ, Mateo D, Giménez-Roldán S. Exposure to Well Water and Pesticides in Parkinson's Disease: a Case-control Study in the Madrid Area. Mov Disord. 1992;7(2):149-52. PubMed PMID: 1584237.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Exposure to well water and pesticides in Parkinson's disease: a case-control study in the Madrid area. AU - Jiménez-Jiménez,F J, AU - Mateo,D, AU - Giménez-Roldán,S, PY - 1992/1/1/pubmed PY - 1992/1/1/medline PY - 1992/1/1/entrez SP - 149 EP - 52 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov. Disord. VL - 7 IS - 2 N2 - Past exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex-matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p less than 0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future case-control studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically exposed. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/1584237/Exposure_to_well_water_and_pesticides_in_Parkinson's_disease:_a_case_control_study_in_the_Madrid_area_ L2 - https://doi.org/10.1002/mds.870070209 DB - PRIME DP - Unbound Medicine ER -