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Blood lipid and lipoprotein levels: relationships with educational level and region of residence in the French SU.VI.MAX study.
Prev Med. 2005 Jun; 40(6):803-11.PM

Abstract

BACKGROUND

Blood lipid profile of French men and women obtained from the general population is not well known. Furthermore, the association between these lipids, as a function of other potential risk factors for cardiovascular disease, and sociodemographic factors such as age, educational level, and region of residence is not well studied in large samples in Europe.

METHODS

Data on French healthy volunteers, aged between 40 and 65 years for men (n = 5141) and 35 and 65 years for women (n = 7876) were obtained from the "Supplementation en Vitamines et Mineraux Antioxydants" (SU.VI.MAX) study, a primary prevention trial. Baseline blood samples were collected in 1994-1995 and analyzed for cholesterol, triglyceride, apolipoproteins (apo)-B and -A1. The results were analyzed separately for men and women as a function of age, educational level, and area of residence.

RESULTS

Overall, blood lipid levels for men and women did not differ significantly from those reported in other Western industrialized countries. Except for triglyceride in men, all blood lipids were statistically different among ages. In women, cholesterol, apo-A1, and apo-B showed a significant decrease with educational level. Statistical differences were found in both genders between blood lipids and lipoproteins among regions of residence.

CONCLUSIONS

Even if differences between region of residence were found in blood lipid levels, this cannot explain the North-East to South gradient in the prevalence of cardiovascular disease in France nor differences between France and other industrialized Western countries.

Authors+Show Affiliations

Service d'Endocrinologie-Métabolisme, AP-HP, Hôpital Pitié-Salpétrière, 83 Boulevard de l'Hôpital, 75013 Paris, France. eric.bruckert@psl.ap-hop-paris.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15850882

Citation

Bruckert, E, et al. "Blood Lipid and Lipoprotein Levels: Relationships With Educational Level and Region of Residence in the French SU.VI.MAX Study." Preventive Medicine, vol. 40, no. 6, 2005, pp. 803-11.
Bruckert E, Czernichow S, Bertrais S, et al. Blood lipid and lipoprotein levels: relationships with educational level and region of residence in the French SU.VI.MAX study. Prev Med. 2005;40(6):803-11.
Bruckert, E., Czernichow, S., Bertrais, S., Paillard, F., Tichet, J., Galan, P., Castetbon, K., & Hercberg, S. (2005). Blood lipid and lipoprotein levels: relationships with educational level and region of residence in the French SU.VI.MAX study. Preventive Medicine, 40(6), 803-11.
Bruckert E, et al. Blood Lipid and Lipoprotein Levels: Relationships With Educational Level and Region of Residence in the French SU.VI.MAX Study. Prev Med. 2005;40(6):803-11. PubMed PMID: 15850882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Blood lipid and lipoprotein levels: relationships with educational level and region of residence in the French SU.VI.MAX study. AU - Bruckert,E, AU - Czernichow,S, AU - Bertrais,S, AU - Paillard,F, AU - Tichet,J, AU - Galan,P, AU - Castetbon,K, AU - Hercberg,S, PY - 2005/4/27/pubmed PY - 2005/9/7/medline PY - 2005/4/27/entrez SP - 803 EP - 11 JF - Preventive medicine JO - Prev Med VL - 40 IS - 6 N2 - BACKGROUND: Blood lipid profile of French men and women obtained from the general population is not well known. Furthermore, the association between these lipids, as a function of other potential risk factors for cardiovascular disease, and sociodemographic factors such as age, educational level, and region of residence is not well studied in large samples in Europe. METHODS: Data on French healthy volunteers, aged between 40 and 65 years for men (n = 5141) and 35 and 65 years for women (n = 7876) were obtained from the "Supplementation en Vitamines et Mineraux Antioxydants" (SU.VI.MAX) study, a primary prevention trial. Baseline blood samples were collected in 1994-1995 and analyzed for cholesterol, triglyceride, apolipoproteins (apo)-B and -A1. The results were analyzed separately for men and women as a function of age, educational level, and area of residence. RESULTS: Overall, blood lipid levels for men and women did not differ significantly from those reported in other Western industrialized countries. Except for triglyceride in men, all blood lipids were statistically different among ages. In women, cholesterol, apo-A1, and apo-B showed a significant decrease with educational level. Statistical differences were found in both genders between blood lipids and lipoproteins among regions of residence. CONCLUSIONS: Even if differences between region of residence were found in blood lipid levels, this cannot explain the North-East to South gradient in the prevalence of cardiovascular disease in France nor differences between France and other industrialized Western countries. SN - 0091-7435 UR - https://www.unboundmedicine.com/medline/citation/15850882/Blood_lipid_and_lipoprotein_levels:_relationships_with_educational_level_and_region_of_residence_in_the_French_SU_VI_MAX_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0091-7435(04)00479-7 DB - PRIME DP - Unbound Medicine ER -