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Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies.
Prev Med. 2005 Jun; 40(6):867-71.PM

Abstract

BACKGROUND

Upon discovering an NTD incidence rate of 27/10,000 in a Texas border county, the Texas Department of Health initiated folic acid intervention for prevention of recurrent NTDs in this predominantly Mexican-American population. This paper describes compliance of this population with USPHS folic acid recommendations and the impact of supplementation on pregnancy outcomes.

METHODS

Based upon information from active surveillance, field teams personally contacted women having NTD-affected pregnancies to enroll them in FA intervention. Enrollees were provided FA at home visits at 3-month intervals throughout the project.

RESULTS

Of 405 women identified with NTD-affected pregnancies, 299 (73.8%) enrolled in the intervention. One hundred ninety-three pregnancies occurred among 138 women. FA supplementation of 0.4 mg/day or more occurred during the last month preconception in 161 (83.4%) of the 193 pregnancies. No NTDs were detected in the 130 livebirths to women who received supplementation nor were NTDs detected in the 23 supplemented women who experienced pregnancy loss.

CONCLUSIONS

Supplementation was successful in preventing recurrent NTDs in Mexican-American women.

Authors+Show Affiliations

Felkner M
Texas Department of Health, Austin, TX, USA. marilyn.felkner@tdh.state.tx.us
Suarez L
No affiliation info available
Hendricks K
No affiliation info available
Larsen R
No affiliation info available

MeSH

AdultCase-Control StudiesCohort StudiesDietary SupplementsFemaleFolic AcidFollow-Up StudiesGestational AgeHumansIncidenceMaternal AgeMexican AmericansNeural Tube DefectsParityPregnancyPregnancy, High-RiskPrenatal CareProbabilityReference ValuesRisk AssessmentTreatment Outcome

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15850889

Citation

Felkner, Marilyn, et al. "Implementation and Outcomes of Recommended Folic Acid Supplementation in Mexican-American Women With Prior Neural Tube Defect-affected Pregnancies." Preventive Medicine, vol. 40, no. 6, 2005, pp. 867-71.
Felkner M, Suarez L, Hendricks K, et al. Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies. Prev Med. 2005;40(6):867-71.
Felkner, M., Suarez, L., Hendricks, K., & Larsen, R. (2005). Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies. Preventive Medicine, 40(6), 867-71.
Felkner M, et al. Implementation and Outcomes of Recommended Folic Acid Supplementation in Mexican-American Women With Prior Neural Tube Defect-affected Pregnancies. Prev Med. 2005;40(6):867-71. PubMed PMID: 15850889.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Implementation and outcomes of recommended folic acid supplementation in Mexican-American women with prior neural tube defect-affected pregnancies. AU - Felkner,Marilyn, AU - Suarez,Lucina, AU - Hendricks,Kate, AU - Larsen,Russell, PY - 2005/4/27/pubmed PY - 2005/9/7/medline PY - 2005/4/27/entrez SP - 867 EP - 71 JF - Preventive medicine JO - Prev Med VL - 40 IS - 6 N2 - BACKGROUND: Upon discovering an NTD incidence rate of 27/10,000 in a Texas border county, the Texas Department of Health initiated folic acid intervention for prevention of recurrent NTDs in this predominantly Mexican-American population. This paper describes compliance of this population with USPHS folic acid recommendations and the impact of supplementation on pregnancy outcomes. METHODS: Based upon information from active surveillance, field teams personally contacted women having NTD-affected pregnancies to enroll them in FA intervention. Enrollees were provided FA at home visits at 3-month intervals throughout the project. RESULTS: Of 405 women identified with NTD-affected pregnancies, 299 (73.8%) enrolled in the intervention. One hundred ninety-three pregnancies occurred among 138 women. FA supplementation of 0.4 mg/day or more occurred during the last month preconception in 161 (83.4%) of the 193 pregnancies. No NTDs were detected in the 130 livebirths to women who received supplementation nor were NTDs detected in the 23 supplemented women who experienced pregnancy loss. CONCLUSIONS: Supplementation was successful in preventing recurrent NTDs in Mexican-American women. SN - 0091-7435 UR - https://www.unboundmedicine.com/medline/citation/15850889/Implementation_and_outcomes_of_recommended_folic_acid_supplementation_in_Mexican_American_women_with_prior_neural_tube_defect_affected_pregnancies_ DB - PRIME DP - Unbound Medicine ER -