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Screening for celiac disease in patients with autoimmune thyroid disease: from research studies to daily clinical practice.
Ann Ital Med Int 2005 Jan-Mar; 20(1):39-44AI

Abstract

Screening procedures performed in research-setting studies have shown that the prevalence of celiac disease in patients with autoimmune thyroid disease is approximately 4-15 times higher than the general population, thus suggesting that patients with autoimmune thyroid disease should be routinely screened for celiac disease. However, the performance of these screening programs has never been evaluated in everyday, clinical-practice setting. We invited newly diagnosed patients with autoimmune thyroid disease, seen at our Hospital, to participate in a serological screening for celiac disease. Two-hundred and thirty-one patients, female to male ratio 8.89:1, mean age 41.3 +/- 18.1 years, range 7.1-80.5 years were included. The number of diagnosed celiac disease was 0. Our results do not support the usefulness of a screening for celiac disease in patients with autoimmune thyroid disease in daily practice, despite the favorable results obtained in research-setting studies. Since screening is a resource-consuming activity, for both patients and clinicians, we suggest that a careful evaluation of the yield of a screening is always warranted before its adoption in the clinical practice.

Authors+Show Affiliations

Istituto di Clinica Medica, Università degli Studi di Sassari. gfanciu@uniss.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15859393

Citation

Fanciulli, Giuseppe, et al. "Screening for Celiac Disease in Patients With Autoimmune Thyroid Disease: From Research Studies to Daily Clinical Practice." Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna, vol. 20, no. 1, 2005, pp. 39-44.
Fanciulli G, Tomasi PA, Caucci F, et al. Screening for celiac disease in patients with autoimmune thyroid disease: from research studies to daily clinical practice. Ann Ital Med Int. 2005;20(1):39-44.
Fanciulli, G., Tomasi, P. A., Caucci, F., Lai, E., Sanciu, F., & Delitala, G. (2005). Screening for celiac disease in patients with autoimmune thyroid disease: from research studies to daily clinical practice. Annali Italiani Di Medicina Interna : Organo Ufficiale Della Societa Italiana Di Medicina Interna, 20(1), pp. 39-44.
Fanciulli G, et al. Screening for Celiac Disease in Patients With Autoimmune Thyroid Disease: From Research Studies to Daily Clinical Practice. Ann Ital Med Int. 2005;20(1):39-44. PubMed PMID: 15859393.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for celiac disease in patients with autoimmune thyroid disease: from research studies to daily clinical practice. AU - Fanciulli,Giuseppe, AU - Tomasi,Paolo A, AU - Caucci,Fabrizia, AU - Lai,Elisabetta, AU - Sanciu,Franca, AU - Delitala,Giuseppe, PY - 2005/4/30/pubmed PY - 2005/12/31/medline PY - 2005/4/30/entrez SP - 39 EP - 44 JF - Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna JO - Ann. Ital. Med. Int. VL - 20 IS - 1 N2 - Screening procedures performed in research-setting studies have shown that the prevalence of celiac disease in patients with autoimmune thyroid disease is approximately 4-15 times higher than the general population, thus suggesting that patients with autoimmune thyroid disease should be routinely screened for celiac disease. However, the performance of these screening programs has never been evaluated in everyday, clinical-practice setting. We invited newly diagnosed patients with autoimmune thyroid disease, seen at our Hospital, to participate in a serological screening for celiac disease. Two-hundred and thirty-one patients, female to male ratio 8.89:1, mean age 41.3 +/- 18.1 years, range 7.1-80.5 years were included. The number of diagnosed celiac disease was 0. Our results do not support the usefulness of a screening for celiac disease in patients with autoimmune thyroid disease in daily practice, despite the favorable results obtained in research-setting studies. Since screening is a resource-consuming activity, for both patients and clinicians, we suggest that a careful evaluation of the yield of a screening is always warranted before its adoption in the clinical practice. SN - 0393-9340 UR - https://www.unboundmedicine.com/medline/citation/15859393/Screening_for_celiac_disease_in_patients_with_autoimmune_thyroid_disease:_from_research_studies_to_daily_clinical_practice_ L2 - http://www.diseaseinfosearch.org/result/1186 DB - PRIME DP - Unbound Medicine ER -