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Reevaluation of stringent low iodine diet in outpatient preparation for radioiodine examination and therapy.
Endocr J 2005; 52(2):237-40EJ

Abstract

To decrease total body iodine is a key point in preparation for radioiodine study and therapy. We introduced a stringent self-managed low iodine diet (LID) and compared the outcome to that of the conventional restricted iodine diet (RID) for outpatients. We measured urine iodine to creatinine ratios (I/Cr) in patients prepared with RID for one week, LID for one week, or LID for two weeks. Mean urinary iodine excretion after RID for one week (n = 210) was 182.2 microg/gCr (range, 13-986 microg/gCr; standard deviation (SD) = 158.5) not reaching below the recommended level (I/Cr<100 microg/gCr). Urinary iodine excretion after LID for one week (n = 15) showed a lower mean urinary iodine level (I/Cr 119.4 microg/gCr; range, 23-218 microg/gCr; SD = 55.9) than RID for one-week, and two-week LID (n = 17) showed an even lower mean level (I/Cr 63.1 microg/gCr; range, 7-134 microg/gCr; SD = 38.7). The one-week LID period adequately (recommended level of I/Cr being less than 100 microg/gCr) prepared 26% of the patients, while two-weeks on the diet adequately prepared 70% of the patients. Furthermore, none of the two-week LID patients had I/Cr>150 microg/gCr, although a significantly greater number of one-week LID patients (19%) did. Our self-managed, outpatient LID successfully induced iodine deficiency, and two-week LID may be recommended for preparation in radioiodine study and therapy for thyroid cancer.

Authors+Show Affiliations

Kuma Hospital, Shimoyamate-dori, Kobe, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15863954

Citation

Tomoda, Chisato, et al. "Reevaluation of Stringent Low Iodine Diet in Outpatient Preparation for Radioiodine Examination and Therapy." Endocrine Journal, vol. 52, no. 2, 2005, pp. 237-40.
Tomoda C, Uruno T, Takamura Y, et al. Reevaluation of stringent low iodine diet in outpatient preparation for radioiodine examination and therapy. Endocr J. 2005;52(2):237-40.
Tomoda, C., Uruno, T., Takamura, Y., Ito, Y., Miya, A., Kobayashi, K., ... Miyauchi, A. (2005). Reevaluation of stringent low iodine diet in outpatient preparation for radioiodine examination and therapy. Endocrine Journal, 52(2), pp. 237-40.
Tomoda C, et al. Reevaluation of Stringent Low Iodine Diet in Outpatient Preparation for Radioiodine Examination and Therapy. Endocr J. 2005;52(2):237-40. PubMed PMID: 15863954.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reevaluation of stringent low iodine diet in outpatient preparation for radioiodine examination and therapy. AU - Tomoda,Chisato, AU - Uruno,Takashi, AU - Takamura,Yuuki, AU - Ito,Yasuhiro, AU - Miya,Akihiro, AU - Kobayashi,Kaoru, AU - Matsuzuka,Fumio, AU - Amino,Nobuyuki, AU - Kuma,Kanji, AU - Miyauchi,Akira, PY - 2005/5/3/pubmed PY - 2005/11/8/medline PY - 2005/5/3/entrez SP - 237 EP - 40 JF - Endocrine journal JO - Endocr. J. VL - 52 IS - 2 N2 - To decrease total body iodine is a key point in preparation for radioiodine study and therapy. We introduced a stringent self-managed low iodine diet (LID) and compared the outcome to that of the conventional restricted iodine diet (RID) for outpatients. We measured urine iodine to creatinine ratios (I/Cr) in patients prepared with RID for one week, LID for one week, or LID for two weeks. Mean urinary iodine excretion after RID for one week (n = 210) was 182.2 microg/gCr (range, 13-986 microg/gCr; standard deviation (SD) = 158.5) not reaching below the recommended level (I/Cr<100 microg/gCr). Urinary iodine excretion after LID for one week (n = 15) showed a lower mean urinary iodine level (I/Cr 119.4 microg/gCr; range, 23-218 microg/gCr; SD = 55.9) than RID for one-week, and two-week LID (n = 17) showed an even lower mean level (I/Cr 63.1 microg/gCr; range, 7-134 microg/gCr; SD = 38.7). The one-week LID period adequately (recommended level of I/Cr being less than 100 microg/gCr) prepared 26% of the patients, while two-weeks on the diet adequately prepared 70% of the patients. Furthermore, none of the two-week LID patients had I/Cr>150 microg/gCr, although a significantly greater number of one-week LID patients (19%) did. Our self-managed, outpatient LID successfully induced iodine deficiency, and two-week LID may be recommended for preparation in radioiodine study and therapy for thyroid cancer. SN - 0918-8959 UR - https://www.unboundmedicine.com/medline/citation/15863954/Reevaluation_of_stringent_low_iodine_diet_in_outpatient_preparation_for_radioiodine_examination_and_therapy_ L2 - https://joi.jlc.jst.go.jp/JST.JSTAGE/endocrj/52.237?from=PubMed DB - PRIME DP - Unbound Medicine ER -