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Prospective study of dietary fat and risk of cataract extraction among US women.
Am J Epidemiol 2005; 161(10):948-59AJ

Abstract

The authors examined prospectively the association between dietary fat intake and cataract extraction in adult women from the Nurses' Health Study. A total of 71,083 women were followed prospectively for up to 16 years between 1984 and 2000. Dietary fat was assessed by repeated food frequency questionnaires. Incident cases of cataract extraction were determined by a biennial questionnaire. The multivariate-adjusted relative risk for the highest compared with the lowest quintile of total fat intake was 1.10 (95% confidence interval (CI): 0.99, 1.22; p(trend) = 0.01). Women in the highest quintile of long-chain omega-3 fatty acid had a 12% lower risk of cataract extraction compared with those in the lowest quintile (relative risk = 0.88, 95% CI: 0.79, 0.98; p(trend) = 0.02). Total fish intake was inversely associated with cataract (for intake of > or = 3/week vs. <1/month: relative risk = 0.89, 95% CI: 0.81, 0.98; p(trend) = 0.01). The authors' findings suggest that higher intake of long-chain omega-3 fatty acid (eicosapentaenoic acid and docosahexaenoic acid) and consumption of fish may modestly reduce the risk of cataract.

Authors+Show Affiliations

Nutritional Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15870159

Citation

Lu, Minyi, et al. "Prospective Study of Dietary Fat and Risk of Cataract Extraction Among US Women." American Journal of Epidemiology, vol. 161, no. 10, 2005, pp. 948-59.
Lu M, Cho E, Taylor A, et al. Prospective study of dietary fat and risk of cataract extraction among US women. Am J Epidemiol. 2005;161(10):948-59.
Lu, M., Cho, E., Taylor, A., Hankinson, S. E., Willett, W. C., & Jacques, P. F. (2005). Prospective study of dietary fat and risk of cataract extraction among US women. American Journal of Epidemiology, 161(10), pp. 948-59.
Lu M, et al. Prospective Study of Dietary Fat and Risk of Cataract Extraction Among US Women. Am J Epidemiol. 2005 May 15;161(10):948-59. PubMed PMID: 15870159.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective study of dietary fat and risk of cataract extraction among US women. AU - Lu,Minyi, AU - Cho,Eunyoung, AU - Taylor,Allen, AU - Hankinson,Susan E, AU - Willett,Walter C, AU - Jacques,Paul F, PY - 2005/5/5/pubmed PY - 2005/6/29/medline PY - 2005/5/5/entrez SP - 948 EP - 59 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 161 IS - 10 N2 - The authors examined prospectively the association between dietary fat intake and cataract extraction in adult women from the Nurses' Health Study. A total of 71,083 women were followed prospectively for up to 16 years between 1984 and 2000. Dietary fat was assessed by repeated food frequency questionnaires. Incident cases of cataract extraction were determined by a biennial questionnaire. The multivariate-adjusted relative risk for the highest compared with the lowest quintile of total fat intake was 1.10 (95% confidence interval (CI): 0.99, 1.22; p(trend) = 0.01). Women in the highest quintile of long-chain omega-3 fatty acid had a 12% lower risk of cataract extraction compared with those in the lowest quintile (relative risk = 0.88, 95% CI: 0.79, 0.98; p(trend) = 0.02). Total fish intake was inversely associated with cataract (for intake of > or = 3/week vs. <1/month: relative risk = 0.89, 95% CI: 0.81, 0.98; p(trend) = 0.01). The authors' findings suggest that higher intake of long-chain omega-3 fatty acid (eicosapentaenoic acid and docosahexaenoic acid) and consumption of fish may modestly reduce the risk of cataract. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/15870159/full_citation L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/aje/kwi118 DB - PRIME DP - Unbound Medicine ER -