Tags

Type your tag names separated by a space and hit enter

Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid.
Biosens Bioelectron. 2006 Jan 15; 21(7):1086-92.BB

Abstract

A stable electroactive thin film of poly(caffeic acid) has been deposited on the surface of a glassy carbon electrode by potentiostatic technique in an aqueous solution containing caffeic acid. Poly(caffeic acid) was used as a modified electrode for the detection of ascorbic acid (AA), epinephrine (EP), uric acid (UA) and their mixture by cyclic voltammetry. This modified electrode exhibits potent and persistent electron-mediating behavior followed by well-separated oxidation peaks towards AA, EP and UA with activation overpotential. For the ternary mixture containing AA, EP and UA, the three compounds can well separate from each other at the scan rate of 20 mVs(-1) with a potential difference of 156, 132 and 288 mV between AA and EP, EP and UA and AA and UA, respectively, which was large enough to determine AA, EP and UA individually and simultaneously. The catalytic peak current obtained, was linearly dependent on the AA, EP and UA concentrations in the range of 2.0 x 10(-5) to 1.0 x 10(-3) mol l(-1), 2.0 x 10(-6) to 8.0 x 10(-5) mol l(-1) and 5.0 x 10(-6) to 3.0 x 10(-4) mol l(-1), and the detection limits for AA, EP and UA were 7.0 x 10(-6), 2.0 x 10(-7) and 6.0 x 10(-7) mol l(-1), respectively. The modified electrode shows good sensitivity, selectivity and stability, and has been applied to the determination of EP in practical injection samples and that of EP, UA and AA simultaneously with satisfactory results.

Authors+Show Affiliations

Ren W
School of Chemistry and Chemical Engineering, Southwest China Normal University, Chongqing 400715, China.
Luo HQ
No affiliation info available
Li NB
No affiliation info available

MeSH

Ascorbic AcidBiosensing TechniquesCaffeic AcidsCarbonCoated Materials, BiocompatibleComplex MixturesElectrochemistryEpinephrineGlassMicroelectrodesUric Acid

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15871920

Citation

Ren, Wang, et al. "Simultaneous Voltammetric Measurement of Ascorbic Acid, Epinephrine and Uric Acid at a Glassy Carbon Electrode Modified With Caffeic Acid." Biosensors & Bioelectronics, vol. 21, no. 7, 2006, pp. 1086-92.
Ren W, Luo HQ, Li NB. Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. Biosens Bioelectron. 2006;21(7):1086-92.
Ren, W., Luo, H. Q., & Li, N. B. (2006). Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. Biosensors & Bioelectronics, 21(7), 1086-92.
Ren W, Luo HQ, Li NB. Simultaneous Voltammetric Measurement of Ascorbic Acid, Epinephrine and Uric Acid at a Glassy Carbon Electrode Modified With Caffeic Acid. Biosens Bioelectron. 2006 Jan 15;21(7):1086-92. PubMed PMID: 15871920.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Simultaneous voltammetric measurement of ascorbic acid, epinephrine and uric acid at a glassy carbon electrode modified with caffeic acid. AU - Ren,Wang, AU - Luo,Hong Qun, AU - Li,Nian Bing, PY - 2005/01/28/received PY - 2005/04/05/revised PY - 2005/04/08/accepted PY - 2005/5/6/pubmed PY - 2006/3/18/medline PY - 2005/5/6/entrez SP - 1086 EP - 92 JF - Biosensors & bioelectronics JO - Biosens Bioelectron VL - 21 IS - 7 N2 - A stable electroactive thin film of poly(caffeic acid) has been deposited on the surface of a glassy carbon electrode by potentiostatic technique in an aqueous solution containing caffeic acid. Poly(caffeic acid) was used as a modified electrode for the detection of ascorbic acid (AA), epinephrine (EP), uric acid (UA) and their mixture by cyclic voltammetry. This modified electrode exhibits potent and persistent electron-mediating behavior followed by well-separated oxidation peaks towards AA, EP and UA with activation overpotential. For the ternary mixture containing AA, EP and UA, the three compounds can well separate from each other at the scan rate of 20 mVs(-1) with a potential difference of 156, 132 and 288 mV between AA and EP, EP and UA and AA and UA, respectively, which was large enough to determine AA, EP and UA individually and simultaneously. The catalytic peak current obtained, was linearly dependent on the AA, EP and UA concentrations in the range of 2.0 x 10(-5) to 1.0 x 10(-3) mol l(-1), 2.0 x 10(-6) to 8.0 x 10(-5) mol l(-1) and 5.0 x 10(-6) to 3.0 x 10(-4) mol l(-1), and the detection limits for AA, EP and UA were 7.0 x 10(-6), 2.0 x 10(-7) and 6.0 x 10(-7) mol l(-1), respectively. The modified electrode shows good sensitivity, selectivity and stability, and has been applied to the determination of EP in practical injection samples and that of EP, UA and AA simultaneously with satisfactory results. SN - 0956-5663 UR - https://www.unboundmedicine.com/medline/citation/15871920/Simultaneous_voltammetric_measurement_of_ascorbic_acid_epinephrine_and_uric_acid_at_a_glassy_carbon_electrode_modified_with_caffeic_acid_ DB - PRIME DP - Unbound Medicine ER -
Grapherence [↓8]

Related Citations

More