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Functional outcome of intrathecal baclofen administration for severe spasticity.
Clin Neurol Neurosurg 2005; 107(4):289-95CN

Abstract

PURPOSE

To estimate the functional benefit in patients with severe spasticity treated with intrathecal baclofen infusion through an implantable pump and to stress the need for functional assessment of these patients with a functional scale.

PATIENTS AND METHODS

Between 1999 and 2003, 22 patients with a long history of severe and disabling pharmaceutically intractable spasticity, underwent implantation of a pump for continuous intrathecal baclofen infusion. The patients were subdivided into two categories according to the aetiology of spasticity: 15 had Multiple Sclerosis and seven had suffered a Spinal Cord Injury at different levels (from C4 to T11). Clinical status was assessed with the Ashworth and Penn spasm scales. Functional benefits were evaluated with the Barthel index score and pain relief with a self-reported visual analogue pain scale.

RESULTS

Postoperatively, all patients presented improvement in spasticity, reduction of spasm frequency, significant improvement in functional status, enhancement of life comfort and reduction of pain.

CONCLUSION

Reduction of spasticity and spasms achieved with intrathecally delivered baclofen, leads to functional improvement and pain relief.

Authors+Show Affiliations

Department of Neurosurgery, Evangelismos General Hospital, University of Athens Medical School, 61 Ipsilantou Street, Kolonaki, Athens 11521, Greece. eboviats@med.uoa.grNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15885386

Citation

Boviatsis, Efstathios J., et al. "Functional Outcome of Intrathecal Baclofen Administration for Severe Spasticity." Clinical Neurology and Neurosurgery, vol. 107, no. 4, 2005, pp. 289-95.
Boviatsis EJ, Kouyialis AT, Korfias S, et al. Functional outcome of intrathecal baclofen administration for severe spasticity. Clin Neurol Neurosurg. 2005;107(4):289-95.
Boviatsis, E. J., Kouyialis, A. T., Korfias, S., & Sakas, D. E. (2005). Functional outcome of intrathecal baclofen administration for severe spasticity. Clinical Neurology and Neurosurgery, 107(4), pp. 289-95.
Boviatsis EJ, et al. Functional Outcome of Intrathecal Baclofen Administration for Severe Spasticity. Clin Neurol Neurosurg. 2005;107(4):289-95. PubMed PMID: 15885386.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Functional outcome of intrathecal baclofen administration for severe spasticity. AU - Boviatsis,Efstathios J, AU - Kouyialis,Andreas T, AU - Korfias,Stefanos, AU - Sakas,Damianos E, PY - 2004/06/21/received PY - 2004/08/23/revised PY - 2004/09/02/accepted PY - 2005/5/12/pubmed PY - 2005/7/27/medline PY - 2005/5/12/entrez SP - 289 EP - 95 JF - Clinical neurology and neurosurgery JO - Clin Neurol Neurosurg VL - 107 IS - 4 N2 - PURPOSE: To estimate the functional benefit in patients with severe spasticity treated with intrathecal baclofen infusion through an implantable pump and to stress the need for functional assessment of these patients with a functional scale. PATIENTS AND METHODS: Between 1999 and 2003, 22 patients with a long history of severe and disabling pharmaceutically intractable spasticity, underwent implantation of a pump for continuous intrathecal baclofen infusion. The patients were subdivided into two categories according to the aetiology of spasticity: 15 had Multiple Sclerosis and seven had suffered a Spinal Cord Injury at different levels (from C4 to T11). Clinical status was assessed with the Ashworth and Penn spasm scales. Functional benefits were evaluated with the Barthel index score and pain relief with a self-reported visual analogue pain scale. RESULTS: Postoperatively, all patients presented improvement in spasticity, reduction of spasm frequency, significant improvement in functional status, enhancement of life comfort and reduction of pain. CONCLUSION: Reduction of spasticity and spasms achieved with intrathecally delivered baclofen, leads to functional improvement and pain relief. SN - 0303-8467 UR - https://www.unboundmedicine.com/medline/citation/15885386/Functional_outcome_of_intrathecal_baclofen_administration_for_severe_spasticity_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0303-8467(04)00132-5 DB - PRIME DP - Unbound Medicine ER -