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Pathological substrate of dementia in Parkinson's disease--its relation to DLB and DLBD.
Parkinsonism Relat Disord. 2005 Jun; 11 Suppl 1:S41-5.PR

Abstract

The pathological background of dementia in Parkinson's disease (PD) has been a matter of controversy. Recent studies have revealed the appearance of many Lewy bodies in the cerebral cortex of PD with dementia (PDD). This pathological change corresponds to the neocortical type, which was originally reported as diffuse Lewy body disease (DLBD), or a transitional type of dementia with Lewy bodies (DLB). Clinical differentiation between DLBD and the transitional type of Lewy body disease (LBD) is sometimes difficult because the symptoms overlap. Therefore, it is appropriate, at least at present, that DLB and PDD are used as clinical diagnoses and that DLBD and the transitional- and brainstem-types of LBD are used as neuropathological diagnoses.

Authors+Show Affiliations

Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan. h_mori@med.juntendo.ac.jp

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15885628

Citation

Mori, Hideo. "Pathological Substrate of Dementia in Parkinson's Disease--its Relation to DLB and DLBD." Parkinsonism & Related Disorders, vol. 11 Suppl 1, 2005, pp. S41-5.
Mori H. Pathological substrate of dementia in Parkinson's disease--its relation to DLB and DLBD. Parkinsonism Relat Disord. 2005;11 Suppl 1:S41-5.
Mori, H. (2005). Pathological substrate of dementia in Parkinson's disease--its relation to DLB and DLBD. Parkinsonism & Related Disorders, 11 Suppl 1, S41-5.
Mori H. Pathological Substrate of Dementia in Parkinson's Disease--its Relation to DLB and DLBD. Parkinsonism Relat Disord. 2005;11 Suppl 1:S41-5. PubMed PMID: 15885628.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathological substrate of dementia in Parkinson's disease--its relation to DLB and DLBD. A1 - Mori,Hideo, PY - 2005/01/01/received PY - 2005/02/14/revised PY - 2005/02/19/accepted PY - 2005/5/12/pubmed PY - 2005/7/26/medline PY - 2005/5/12/entrez SP - S41 EP - 5 JF - Parkinsonism & related disorders JO - Parkinsonism Relat Disord VL - 11 Suppl 1 N2 - The pathological background of dementia in Parkinson's disease (PD) has been a matter of controversy. Recent studies have revealed the appearance of many Lewy bodies in the cerebral cortex of PD with dementia (PDD). This pathological change corresponds to the neocortical type, which was originally reported as diffuse Lewy body disease (DLBD), or a transitional type of dementia with Lewy bodies (DLB). Clinical differentiation between DLBD and the transitional type of Lewy body disease (LBD) is sometimes difficult because the symptoms overlap. Therefore, it is appropriate, at least at present, that DLB and PDD are used as clinical diagnoses and that DLBD and the transitional- and brainstem-types of LBD are used as neuropathological diagnoses. SN - 1353-8020 UR - https://www.unboundmedicine.com/medline/citation/15885628/Pathological_substrate_of_dementia_in_Parkinson's_disease__its_relation_to_DLB_and_DLBD_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(05)00041-6 DB - PRIME DP - Unbound Medicine ER -
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