Tags

Type your tag names separated by a space and hit enter

Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure.
J Am Soc Echocardiogr. 2005 May; 18(5):435-44.JA

Abstract

Little is known about the prognostic importance of right ventricular (RV) systolic and diastolic function. The purpose of this study was to determine the prognostic power of systolic and diastolic RV functional parameters derived from Doppler tissue imaging of tricuspid annular motion and to assess whether their combination might improve the risk stratification of patients with heart failure. In all, 140 patients with symptomatic heart failure and left ventricular ejection fraction of 40% or less underwent standard echocardiography, Doppler tissue imaging of tricuspid annular motion, and right heart catheterization. They were followed up for a mean period of 17 months for cardiac-related death and nonfatal cardiac events including the implantation of cardioverter-defibrillator and hospitalization for heart failure decompensation. A total of 48 cardiac events occurred; 19 patients died, 26 were hospitalized for heart failure decompensation, and 3 because of the need for implantation of a cardioverter-defibrillator. The peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less, peak early diastolic tricuspid annular velocity of 8.9 cm/s or less, tricuspid annular acceleration during isovolumic contraction of 2.52 m/s 2 or less, and Doppler RV index (Tei index) of 1.20 or more were found to significantly worsen survival or event-free survival. However, their combination significantly exceeded the predictive potential of individual parameters. The worst survival was predicted by the combination of peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less plus peak early diastolic tricuspid annular velocity of 8.9 cm/s or less plus tricuspid annular acceleration during isovolumic contraction of 2.52 m/s 2 or less (relative risk 6.17, P < .001), whereas the worst event-free survival was identified by the combination of peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less plus peak early diastolic tricuspid annular velocity of 8.9 cm/s or less plus Doppler RV index (Tei index) of 1.20 or more (relative risk 3.62, P < .001). In conclusion, the combination of RV systolic and diastolic functional parameters represents a very powerful tool for risk stratification of patients with symptomatic heart failure.

Authors+Show Affiliations

Department of Internal Medicine and the Centere of Biostatics and Analyses, Masaryk University, Brno, Czech Republic. jaroslav.meluzin@fnusa.czNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15891753

Citation

Meluzin, Jaroslav, et al. "Prognostic Importance of Various Echocardiographic Right Ventricular Functional Parameters in Patients With Symptomatic Heart Failure." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, vol. 18, no. 5, 2005, pp. 435-44.
Meluzin J, Spinarová L, Hude P, et al. Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure. J Am Soc Echocardiogr. 2005;18(5):435-44.
Meluzin, J., Spinarová, L., Hude, P., Krejcí, J., Kincl, V., Panovský, R., & Dusek, L. (2005). Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, 18(5), 435-44.
Meluzin J, et al. Prognostic Importance of Various Echocardiographic Right Ventricular Functional Parameters in Patients With Symptomatic Heart Failure. J Am Soc Echocardiogr. 2005;18(5):435-44. PubMed PMID: 15891753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prognostic importance of various echocardiographic right ventricular functional parameters in patients with symptomatic heart failure. AU - Meluzin,Jaroslav, AU - Spinarová,Lenka, AU - Hude,Petr, AU - Krejcí,Jan, AU - Kincl,Vladimír, AU - Panovský,Roman, AU - Dusek,Ladislav, PY - 2005/5/14/pubmed PY - 2005/8/5/medline PY - 2005/5/14/entrez SP - 435 EP - 44 JF - Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography JO - J Am Soc Echocardiogr VL - 18 IS - 5 N2 - Little is known about the prognostic importance of right ventricular (RV) systolic and diastolic function. The purpose of this study was to determine the prognostic power of systolic and diastolic RV functional parameters derived from Doppler tissue imaging of tricuspid annular motion and to assess whether their combination might improve the risk stratification of patients with heart failure. In all, 140 patients with symptomatic heart failure and left ventricular ejection fraction of 40% or less underwent standard echocardiography, Doppler tissue imaging of tricuspid annular motion, and right heart catheterization. They were followed up for a mean period of 17 months for cardiac-related death and nonfatal cardiac events including the implantation of cardioverter-defibrillator and hospitalization for heart failure decompensation. A total of 48 cardiac events occurred; 19 patients died, 26 were hospitalized for heart failure decompensation, and 3 because of the need for implantation of a cardioverter-defibrillator. The peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less, peak early diastolic tricuspid annular velocity of 8.9 cm/s or less, tricuspid annular acceleration during isovolumic contraction of 2.52 m/s 2 or less, and Doppler RV index (Tei index) of 1.20 or more were found to significantly worsen survival or event-free survival. However, their combination significantly exceeded the predictive potential of individual parameters. The worst survival was predicted by the combination of peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less plus peak early diastolic tricuspid annular velocity of 8.9 cm/s or less plus tricuspid annular acceleration during isovolumic contraction of 2.52 m/s 2 or less (relative risk 6.17, P < .001), whereas the worst event-free survival was identified by the combination of peak tricuspid annular velocity during systolic ejection of 10.8 cm/s or less plus peak early diastolic tricuspid annular velocity of 8.9 cm/s or less plus Doppler RV index (Tei index) of 1.20 or more (relative risk 3.62, P < .001). In conclusion, the combination of RV systolic and diastolic functional parameters represents a very powerful tool for risk stratification of patients with symptomatic heart failure. SN - 0894-7317 UR - https://www.unboundmedicine.com/medline/citation/15891753/Prognostic_importance_of_various_echocardiographic_right_ventricular_functional_parameters_in_patients_with_symptomatic_heart_failure_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0894731705001318 DB - PRIME DP - Unbound Medicine ER -